Evidence map›Paper›PMID 34223818›Full record

ArticleeLife2021

Novel LOTUS-domain proteins are organizational hubs that recruit

Patricia Giselle Cipriani, Olivia Bay, John Zinno, Michelle Gutwein, Hin Hark Gan, Vinay K Mayya, George Chung, Jia-Xuan Chen, Hala Fahs, Yu Guan and 4 more

Open access · goldAbstract read
In one paragraph

Article in eLife, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
1.9field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed, 30 citations in OpenAlex.

  1. Article
  2. LOTUS-domain proteins activate Vasa to drive germ granule assembly.bioRxiv : the preprint server for biology · 2026
    Article
  3. Kinetochore components are perinuclear and form condensates inbioRxiv : the preprint server for biology · 2025
    Article
  4. Article
  5. Article
  6. Review
  7. Review
  8. Article
  9. Article
  10. How germ granules promote germ cell fate.Nature reviews. Genetics · 2024
    Review
  11. Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Article
  17. Review
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 4 institutions in 4 countries.

Patricia Giselle CiprianiCenter for Genomics and Systems Biology, Department of Biology, New York University, New York, United States.ORCID 0000-0001-9772-1012
Olivia BayCenter for Genomics and Systems Biology, Department of Biology, New York University, New York, United States.
John ZinnoCenter for Genomics and Systems Biology, Department of Biology, New York University, New York, United States.
Michelle GutweinCenter for Genomics and Systems Biology, Department of Biology, New York University, New York, United States.
Hin Hark GanCenter for Genomics and Systems Biology, Department of Biology, New York University, New York, United States.
Vinay K MayyaGoodman Cancer Research Centre and Department of Biochemistry, McGill University, Montreal, Canada.
George ChungCenter for Genomics and Systems Biology, Department of Biology, New York University, New York, United States.
Jia-Xuan ChenMax Delbrück Center for Molecular Medicine, Berlin, Germany.ORCID 0000-0002-3671-553X
Hala FahsNYU Abu Dhabi Center for Genomics and Systems Biology, New York University Abu Dhabi, Abu Dhabi, United Arab Emirates.
Yu GuanCenter for Genomics and Systems Biology, Department of Biology, New York University, New York, United States.
Thomas F DuchaineGoodman Cancer Research Centre and Department of Biochemistry, McGill University, Montreal, Canada.
Matthias SelbachMax Delbrück Center for Molecular Medicine, Berlin, Germany.
Fabio PianoCenter for Genomics and Systems Biology, Department of Biology, New York University, New York, United States.
Kristin C GunsalusCenter for Genomics and Systems Biology, Department of Biology, New York University, New York, United States.ORCID 0000-0001-9769-4624
New York University · USNew York University Abu Dhabi · AEMax Delbrück Center · DEMcGill University Health Centre · CA

Funding

Enhancing and expanding the CGC Strain CollectionP40OD010440 · OD · UNIVERSITY OF MINNESOTA · PI Ann E. Rougvie · 2012 to 2026
$7.5M
CIHR MOP 123352NIH HHS P40 OD010440
6 · The paper itself

Abstract

We describe MIP-1 and MIP-2, novel paralogous

Indexed as

AnimalsCaenorhabditis elegansCaenorhabditis elegans ProteinsDEAD-box RNA HelicasesGene Expression RegulationGerm CellsIntracellular Signaling Peptides and ProteinsCaenorhabditis elegans ProteinsDEAD-box RNA HelicasesGLH-1 protein, C elegansIntracellular Signaling Peptides and ProteinsMEG-3 protein, C elegansmip-1 protein, C elegansC. eleganscell biologydevelopmental biologygerm granulesIDRLOTUSP granulesphase separationvasa

Identifiers

PMID34223818
PMCPMC8331183
OpenAlexW3180786199

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.