Evidence map›Paper›PMID 34223563›Full record

ArticleMedical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention2020

Characterizing Intra-soma Diffusion with Spherical Mean Spectrum Imaging.

Khoi Minh Huynh, Ye Wu, Kim-Han Thung, Sahar Ahmad, Hoyt Patrick Taylor, Dinggang Shen, Pew-Thian Yap

Abstract read
In one paragraph

Article in Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Microstructure Fingerprinting for Heterogeneously Oriented Tissue Microenvironments.Medical image computing and computer-assisted intervention : MICCAI ... International Conference on Medical Image Computing and Computer-Assisted Intervention · 2023
    Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Khoi Minh HuynhDepartment of Biomedical Engineering, University of North Carolina, Chapel Hill, USA.
Ye WuDepartment of Radiology and Biomedical Research Imaging Center, University of North Carolina, Chapel Hill, USA.
Kim-Han ThungDepartment of Radiology and Biomedical Research Imaging Center, University of North Carolina, Chapel Hill, USA.
Sahar AhmadDepartment of Radiology and Biomedical Research Imaging Center, University of North Carolina, Chapel Hill, USA.
Hoyt Patrick TaylorDepartment of Radiology and Biomedical Research Imaging Center, University of North Carolina, Chapel Hill, USA.
Dinggang ShenDepartment of Biomedical Engineering, University of North Carolina, Chapel Hill, USA.
Pew-Thian YapDepartment of Biomedical Engineering, University of North Carolina, Chapel Hill, USA.

Funding

Diagnosis of Alzheimer's Disease Using Dynamic High-Order Brain NetworksR01EB022880 · NIBIB · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2016 to 2018
$1.1M
Robust White Matter Morphometry with Small DatabasesR01NS093842 · NINDS · UNIV OF NORTH CAROLINA CHAPEL HILL · PI YAP, PEW-THIAN · 2016 to 2018
$1.1M
NIBIB NIH HHS R01 EB022880NINDS NIH HHS R01 NS093842
6 · The paper itself

Abstract

Most brain microstructure models are dedicated to the quantification of white matter microstructure, using for example sticks, cylinders, and zeppelins to model intra- and extra-axonal environments. Gray matter presents unique micro-architecture with cell bodies (somas) exhibiting diffusion characteristics that differ from axons in white matter. In this paper, we introduce a method to quantify soma microstructure, giving measures such as volume fraction, diffusivity, and kurtosis. Our method captures a spectrum of diffusion patterns and scales and does not rely on restrictive model assumptions. We show that our method yields unique and meaningful contrasts that are in agreement with histological data. We demonstrate its application in the mapping of the distinct spatial patterns of soma density in the cortex.

Identifiers

PMID34223563
PMCPMC8248904

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.