ArticleNeurotrauma reports2020
Mild and Moderate Traumatic Brain Injury and Repeated Stress Affect Corticosterone in the Rat.
Article in Neurotrauma reports, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 21 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
21 citing papers in PubMed.
- Pediatric traumatic brain injury elicits acute neuroinflammation and long-term changes in social, cognitive, and decision-making behaviors in male and female rats.bioRxiv : the preprint server for biology · 2026Article
- HSV-1 reactivation as an emergent property of neuronal stress: implications for traumatic brain injury.Journal of neuroinflammation · 2026Review
- Stem cells ameliorate neurotrauma-induced visual disturbances and retinal degeneration via broad normalization of β-catenin-related signaling.International journal of medical sciences · 2026Article
- Sex hormone dysregulation after traumatic brain injury: interactions with sleep disturbances and seizure susceptibility.Frontiers in neuroscience · 2026Review
- Effects of Subanesthetic Intravenous Ketamine Infusion on Stress Hormones and Synaptic Density in Rats with Mild Closed-Head Injury.Biomedicines · 2025Article
- Extracranial Effects of Traumatic Brain Injury: A Narrative Review.Clinics and practice · 2025Review
- Neurobehavioral Abnormalities in Offspring of Young Adult Male Rats With a History of Traumatic Brain Injury.Journal of neurotrauma · 2024Article
- Sex-dependent temporal changes in astrocyte-vessel interactions following diffuse traumatic brain injury in rats.Frontiers in physiology · 2024Article
- Repeated mild traumatic brain injury causes sex-specific increases in cell proliferation and inflammation in juvenile rats.Journal of neuroinflammation · 2023Article
- Article
- High-Fat Diet Exacerbates Stress Responsivity in Juvenile Traumatic Brain Injury.Journal of neurotrauma · 2023Article
- Intergenerational Perioperative Neurocognitive Disorder.Biology · 2023Review
- Intergenerational Perioperative Neurocognitive Disorder in Young Adult Male Rats with Traumatic Brain Injury.Anesthesiology · 2023Article
- Delayed TBI-Induced Neuronal Death in the Ipsilateral Hippocampus and Behavioral Deficits in Rats: Influence of Corticosterone-Dependent Survivorship Bias?International journal of molecular sciences · 2023Article
- Blast Exposure Induces Acute Alterations in Circadian Clock Genes in the Hypothalamus and Pineal Gland in Rats: An Exploratory Study.Neurotrauma reports · 2023Article
- The Neurobiological Links between Stress and Traumatic Brain Injury: A Review of Research to Date.International journal of molecular sciences · 2022Review
- Brain Trauma, Glucocorticoids and Neuroinflammation: Dangerous Liaisons for the Hippocampus.Biomedicines · 2022Review
- Temporal profile of serum metabolites and inflammation following closed head injury in rats is associated with HPA axis hyperactivity.Metabolomics : Official journal of the Metabolomic Society · 2022Article
- Neuroinflammatory Cytokine Response, Neuronal Death, and Microglial Proliferation in the Hippocampus of Rats During the Early Period After Lateral Fluid Percussion-Induced Traumatic Injury of the Neocortex.Molecular neurobiology · 2022Article
- Neurobiological Links between Stress, Brain Injury, and Disease.Oxidative medicine and cellular longevity · 2022Review
Corrections and comments
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Authors and funding
3 authors.
Funding
Abstract
Traumatic brain injury (TBI) survivors suffer from a range of morbidities, including post-traumatic endocrinopathies that can cause physical and mental changes in patients, greatly compromising quality of life. This study tested the hypothesis that mild and moderate diffuse TBI leads to chronic deficiencies in corticosterone (CORT) regulation following repeated exposure to restraint stress over time. Young adult male rats (
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What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.