ArticleResuscitation plus2021
The effect of sex and age on return of spontaneous circulation and survival to hospital discharge in patients with out of hospital cardiac arrest: A retrospective analysis of a Canadian population.
Article in Resuscitation plus, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 15 papers.
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Who cites it
15 citing papers in PubMed.
- Unequal Relief: Sex Disparities in Opioid Use for Cardiac Chest Pain in the Emergency Department.The western journal of emergency medicine · 2026Observational
- Equal cardiac arrest care - a qualitative study of healthcare professionals' experiences.BMC medical ethics · 2026Article
- Sex-based disparities in bystander CPR for out-of-hospital cardiac arrest related to non-prescription drug use.Resuscitation plus · 2026Article
- Medical Student Perspectives on Female Anatomical Representation in CPR Training.Advances in medical education and practice · 2026Article
- Does critical care paramedic deployment improve delivery of post-resuscitation care following out-of-hospital cardiac arrest? A retrospective cohort study.British paramedic journal · 2025Article
- Age and gender disparities in administration of opioid for cardiac chest pain in the emergency department.PloS one · 2025Observational
- Incidence, characteristics, and prehospital outcomes of out-of-hospital cardiac arrest in Qatar: a nationwide gender-based investigation.International journal of emergency medicine · 2024Article
- Factors predicting mortality in the cardiac ICU during the early phase of targeted temperature management in the treatment of post-cardiac arrest syndrome - The RAPID score.Resuscitation plus · 2024Article
- Time Is Life: Golden Ten Minutes on Scene-EuReCa_Serbia 2014-2023.Medicina (Kaunas, Lithuania) · 2024Article
- The interaction of sex and age on outcomes in emergency medical services-treated out-of-hospital cardiac arrest: A 5-year multicenter retrospective analysis.Resuscitation plus · 2024Article
- Provision of bystander CPR for out-of-hospital cardiac arrest in the Middle East: a retrospective gender-based analysis.International journal of emergency medicine · 2023Article
- One-year survival after out-of- hospital cardiac arrest: Sex-based survival analysis in a Canadian population.Journal of the American College of Emergency Physicians open · 2023Article
- Predictors of neurological outcome after out-of-hospital cardiac arrest: sex-based analysis: do males derive greater benefit from hypothermia management than females?International journal of emergency medicine · 2022Article
- Traumatic Injuries Following Mechanical versus Manual Chest Compression.Open access emergency medicine : OAEM · 2022Article
- Sex Differences in Incidence and Outcome of Out-of-Hospital Cardiac Arrest Within a Local Health Network.Frontiers in cardiovascular medicine · 2022Article
Corrections and comments
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Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectivesWe evaluated the effect of sex and age on out-of-hospital cardiac arrest (OHCA) outcomes in a Canadian population.
methodsThis study was a retrospective analysis of the British Columbia (BC) Cardiac Arrest Registry (2011-16). We included adult, non-traumatic, EMS-treated OHCA. We stratified the cohort into four groups by age and sex: younger females (18-47 years of age), younger males (18-47 years of age), older females, and older males (>53 years old). We used logistic regression to examine the effect of sex and interaction effect of sex and age on ROSC and survival to hospital discharge.
resultsWe included 8115 patients; 31.4% were females. Females had a lower proportion of OHCA in public locations, bystander witnessed arrests, and with initial shockable rhythms. Overall, females had greater adjusted odds of ROSC (OR 1.29, 95% CI 1.15-1.42, p < 0.001). The ROSC advantage was significant in females with non-shockable rhythms (OR 1.48, 95% CI 1.24-1.78, p < 0.001) and females of premenopausal age. However, there was no significant difference in survival to hospital discharge between females and males overall or by sex-age groups. Both younger females and younger males have higher odds of survival to hospital discharge compared to older females and males. Older females had the lowest survival rate among all other sex-age groups.
conclusionsFemale sex was associated with ROSC but not survival to hospital discharge. In the post-arrest phase, females, specifically those in the older age group, had a higher death rate, demonstrating the need for sex- and age-specific research in pre-and-post-OHCA care.
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