ArticleResuscitation plus2020
Oxygen use in low-resource settings: An intervention still triggered by intuition.
Article in Resuscitation plus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
2 citing papers in PubMed, 6 citations in OpenAlex.
- Can guidelines rein in oxygen use? A retrospective cross-sectional study using routinely collected data.International journal for quality in health care : journal of the International Society for Quality in Health Care · 2023Article
- Predicting acute clinical deterioration with interpretable machine learning to support emergency care decision making.Scientific reports · 2023Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 2 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundAlthough hypoxic patients attending low-resource hospitals have a high mortality, many are not given supplemental oxygen. If oximetry is not available, then the decision to provide oxygen must be based on other factors.
methodsThe variables associated with the decision to provide supplemental oxygen made by an emergency department staff, without access to oximetry, in a low resource Ugandan hospital were determined from data collected within 16 h of admission to the hospital's medical and surgical wards.
resultsOf 2,599 patients, 731 (28.1%) had an oxygen saturation <95%, and 164 (6.3%) an oxygen saturation <90%. Of the 731 patients with oxygen levels below 95% 573 (83%) were not given oxygen; oxygen was only given to 63 (38%) of the 164 patients with oxygen saturation <90%. On average, a patient given oxygen was more likely to die than one not given oxygen, regardless of their oxygen saturation (odds ratio 13.4, 95%CI 9.1-19.6). After multivariate analysis weakness, dyspnoea, low oxygen saturation, high heart rate, high respiratory rate, low temperature, alertness, gait, and a medical illness were all significantly associated with the use of supplemental oxygen and in-hospital mortality. Logistic regression modelling of these variables had comparable discrimination for both oxygen use (c statistic 0.88 SE 0.02) and in-hospital mortality (c statistic 0.84 SE 0.02).
conclusionThe intuitive decision to provide oxygen was strongly associated with in-hospital mortality, suggesting that oxygen was given to those considered the sickest patients. In the future, oximetry may guide oxygen therapy more efficiently.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.