ReviewResuscitation plus2020
A systematic review of current ECPR protocols. A step towards standardisation.
Review in Resuscitation plus, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 35 papers, 1 of them a synthesis that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
35 citing papers in PubMed, 1 synthesis or guideline pooled it.
- The impact of selection criteria and study design on reported survival outcomes in extracorporeal oxygenation cardiopulmonary resuscitation (ECPR): a systematic review and meta-analysis.Scandinavian journal of trauma, resuscitation and emergency medicine · 2021Pooled it
- The effect of initial rhythm on patient outcome in refractory cardiac arrest requiring extracorporeal cardiopulmonary resuscitation: A retrospective, multicentre registry cohort study.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2026Article
- Assessing accessibility to the extracorporeal cardiopulmonary resuscitation pathway for out-of-hospital cardiac arrests in London.Resuscitation plus · 2026Article
- Time to extracorporeal cardiopulmonary resuscitation flow and outcomes in paediatric in-hospital cardiac arrest: a 12-year single-centre study.Resuscitation plus · 2026Article
- Optimal Low-Flow Time of Extracorporeal Cardiopulmonary Resuscitation for Favorable Neurological Outcomes: A Risk-Stratified Approach.Journal of clinical medicine · 2026Article
- Implementation of emergency extracorporeal membrane oxygenation in a hospital without on-site cardiothoracic surgery support.Resuscitation plus · 2026Article
- Contemporary extracorporeal cardiopulmonary resuscitation programs for cardiac arrest.Frontiers in cardiovascular medicine · 2026Review
- The Pre-ECPR score for predicting favorable neurological outcomes after extracorporeal cardiopulmonary resuscitation: protocol for external validation in the Prague OHCA trial cohort.Resuscitation plus · 2026Article
- Creatine Kinase as a Prognostic Factor for Mortality in Extracorporeal Cardiopulmonary Resuscitation: A Retrospective Observational Study.Journal of clinical medicine · 2025Article
- Impact of extended eligibility criteria on survival after veno-arterial extracorporeal membrane oxygenation for refractory cardiac arrest: a 8-year single-center study.Resuscitation plus · 2025Article
- Database and geospatial mapping study of those eligible for extracorporeal cardiopulmonary resuscitation in the Thames Valley Region, England.Resuscitation plus · 2025Article
- Comparing clinical only and combined clinical laboratory models for ECPR outcomes in refractory cardiac arrest.Scientific reports · 2025Article
- Long-term outcomes of patients who received extracorporeal cardiopulmonary resuscitation (ECPR) following in-hospital cardiac arrest: Analysis of EXCEL registry data.Critical care and resuscitation : journal of the Australasian Academy of Critical Care Medicine · 2024Article
- Enhancing survival in cardiac arrest: the urgent need for optimized extracorporeal cardiopulmonary resuscitation implementation and protocols - editorial.Annals of medicine and surgery (2012) · 2024Article
- Effects of Perfusion, Coronary Artery Disease Burden, and Revascularization in Establishing Organized Cardiac Rhythm During Extracorporeal Cardiopulmonary Resuscitation for Shockable Refractory Out-of-Hospital Cardiac Arrest.Journal of the American Heart Association · 2024Article
- Implementation of Extracorporeal CPR Programs for Out-of-Hospital Cardiac Arrest: Another Tale of Two County Hospitals.Annals of emergency medicine · 2024Article
- Clinicians' experience of barriers and facilitators to care delivery of an extracorporeal cardiopulmonary resuscitation service for out-of-hospital cardiac arrest: a qualitative survey.Scandinavian journal of trauma, resuscitation and emergency medicine · 2024Article
- Article
- A review of pre-hospital extracorporeal cardiopulmonary resuscitation and its potential application in the North East of England.International journal of emergency medicine · 2024Review
- Clinical indications and outcomes of Impella devices for severe cardiogenic shock in COVID-19 patients: a systematic review.Annals of medicine and surgery (2012) · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
aimExtracorporeal cardiopulmonary resuscitation (ECPR) can treat cardiac arrest refractory to conventional therapies. Our goal was to identify the best protocol for survival with good neurological outcome through the evaluation of current inclusion criteria, exclusion criteria, cannulation strategies and additional therapeutic measures.
methodsA systematic literature search was used to identify eligible publications from PubMed, Embase, Web of Science and Cochrane for articles published from 29 June 2009 until 29 June 2019.
resultsThe selection process led to a total of 24 eligible articles, considering 1723 patients in total. A good neurological outcome at hospital discharge was found in 21.3% of all patients. The most consistent criterion for inclusion was refractory cardiac arrest (RCA), used in 21/25 (84%) of the protocols. The preferred cannulation method was the percutaneous Seldinger technique (44%).
conclusionECPR is a feasible option for cardiac arrest and should already be considered in an early stage of CPR. One of the key findings is that time-to-ECPR seems to be correlated with good neurological survival. An important contributing factor is the definition of RCA. Protocols defining RCA as >10 min had a mean good neurological survival of 26.7%. Protocols with a higher cut-off, between 15 and 30 min, had a mean good neurological survival of 14.5%. Another factor contributing to the time-to-ECPR is the preferred access technique. A percutaneous Seldinger technique combined with ultrasonography and fluoroscopic guidance leads to a reduced cannulation time and complication rate. Conclusive research around prehospital cannulation still needs to be conducted.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.