ArticleF&S reports2021
Cost-effectiveness of preimplantation genetic testing for aneuploidy for fresh donor oocyte cycles.
Article in F&S reports, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 30 citations in OpenAlex.
- Cost-effectiveness of preimplantation genetic testing for aneuploidy for women with subfertility in China: an economic evaluation using evidence from the CESE-PGS trial.BMC pregnancy and childbirth · 2023Trial
- Elective single embryo transfer in in vitro fertilization cycles with or without preimplantation genetic testing using next-generation sequencing: A randomized clinical trial.Clinics (Sao Paulo, Brazil) · 2026Article
- United States racial/ethnic disparities in PGT-A use: an analysis of 2014-2020 SART CORS database.Reproductive biology and endocrinology : RB&E · 2025Article
- Overview of ADPKD in Pregnancy.Kidney international reports · 2025Review
- Considerations on optimizing the patient experience during assisted reproductive technology treatment: a qualitative analysis.F&S reports · 2025Article
- Trends and outcomes of fresh and frozen donor oocyte cycles in the United States.Fertility and sterility · 2024Article
- Attitudes, concerns, and perceptions of patients undergoing fertility treatments in an abortion restrictive state in the aftermath of the Roe v. Wade reversal.Journal of assisted reproduction and genetics · 2024Article
- Spinal muscular atrophy genetic epidemiology and the case for premarital genomic screening in Arab populations.Communications medicine · 2024Article
- Systematic review of the economic evaluation model of assisted reproductive technology.Health economics review · 2024Review
- Mosaic embryo transfer versus additional IVF with PGT-A Cycle: a decision model comparing live birth rate and cost.Journal of assisted reproduction and genetics · 2024Article
- Preimplantation genetic testing for sickle cell disease: a cost-effectiveness analysis.F&S reports · 2023Article
- Appropriate whole genome amplification and pathogenic loci detection can improve the accuracy of preimplantation genetic diagnosis for deletional α-thalassemia.Frontiers in endocrinology · 2023Article
- Novel embryo selection strategies-finding the right balance.Frontiers in reproductive health · 2023Article
- Effect of trophectoderm biopsy for PGT-A on live birth rate per embryo in good prognosis patients.Archives of gynecology and obstetrics · 2022Article
- Genetic counseling decisions in gestational carrier pregnancies.Journal of assisted reproduction and genetics · 2022Article
- Valuing infertility treatment: Why QALYs are inadequate, and an alternative approach to cost-effectiveness thresholds.Frontiers in medical technology · 2022Article
- Prevalence and performance of private equity-affiliated fertility practices in the United States.Fertility and sterility · 2022Article
- Preimplantation genetic testing for aneuploidies does not increase success rates in fresh oocyte donation cycles: a paired cohort study.Journal of assisted reproduction and genetics · 2021Article
- Reduction in multiple pregnancy rate in donor oocyte-recipient gestational carrier (GC) in vitro fertilization (IVF) cycles in the USA with single-embryo transfer and preimplantation genetic testing.Journal of assisted reproduction and genetics · 2021Article
- Assessing the Ethical Considerations in the Era of Advanced Prenatal Testing and Genetic Counselling - Clinicians' Perspective.Indian journal of community medicine : official publication of Indian Association of Preventive & Social MedicineArticle
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors at 2 institutions in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveTo determine whether in vitro fertilization (IVF) with preimplantation genetic testing for aneuploidy (PGT-A) is cost effective to achieve a live birth compared with IVF alone in fresh donor oocyte cycles.
designTheoretical cost-effectiveness study.
settingNot applicable. PATIENTS: None.
interventionsComparison between the cost of IVF with PGT-A vs. IVF alone to achieve a live birth. The model analyzed a hypothetical single fresh oocyte donor IVF cycle with PGT-A vs. IVF alone and followed the progression of a single embryo through the different decision nodes. Cost estimates assigned to each clinical event were based on data obtained from the literature and institutional costs.
main outcome measuresCost per live birth.
resultsIn the base-case analysis, IVF with PGT-A was not cost effective in fresh donor oocyte cycles when compared with IVF alone to achieve a live birth. The cycles using PGT-A cost an additional $6,018.66. The incremental cost-effectiveness ratio was found to be $119,606.59 per additional live birth achieved with IVF with PGT-A. Monte Carlo simulations demonstrated that IVF with PGT-A was not cost effective in nearly all iterations.
conclusionsPGT-A in fresh donor oocyte IVF cycles is not cost effective compared with IVF alone over a wide range of probabilities and costs.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.