Evidence map›Paper›PMID 34223176›Full record

ArticleEuropean heart journal. Digital health2021

Automated cardiac volume assessment and cardiac long- and short-axis imaging plane prediction from electrocardiogram-gated computed tomography volumes enabled by deep learning.

Zhennong Chen, Marzia Rigolli, Davis Marc Vigneault, Seth Kligerman, Lewis Hahn, Anna Narezkina, Amanda Craine, Katherine Lowe, Francisco Contijoch

Open access · goldAbstract read
In one paragraph

Article in European heart journal. Digital health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
1.8field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Article
  9. Article
  10. Article
  11. Adopting artificial intelligence in cardiovascular medicine: a scoping review.Hypertension research : official journal of the Japanese Society of Hypertension · 2024
    Article
  12. Article
  13. Article
  14. Article
  15. Deep learning automates detection of wall motion abnormalitiesFrontiers in cardiovascular medicine · 2022
    Article
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Zhennong ChenDepartment of Bioengineering, UC San Diego School of Engineering, 9500 Gilman Drive, MC 0412, La Jolla, CA 92093, USA.ORCID https://orcid.org/0000-0001-6133-8716
Marzia RigolliDepartment of Bioengineering, UC San Diego School of Engineering, 9500 Gilman Drive, MC 0412, La Jolla, CA 92093, USA.
Davis Marc VigneaultDepartment of Internal Medicine, Scripps Mercy Hospital, 4077 Fifth Ave, San Diego, CA 92103, USA.
Seth KligermanDepartment of Radiology, UC San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Lewis HahnDepartment of Radiology, UC San Diego School of Medicine, 9500 Gilman Drive, La Jolla, CA 92093, USA.
Anna NarezkinaDepartment of Medicine, Division of Cardiology, UC San Diego School of Medicine, 9500 Gilman Dr, La Jolla, CA 92093, USA.
Amanda CraineDepartment of Bioengineering, UC San Diego School of Engineering, 9500 Gilman Drive, MC 0412, La Jolla, CA 92093, USA.
Katherine LoweDepartment of Bioengineering, UC San Diego School of Engineering, 9500 Gilman Drive, MC 0412, La Jolla, CA 92093, USA.
Francisco ContijochDepartment of Bioengineering, UC San Diego School of Engineering, 9500 Gilman Drive, MC 0412, La Jolla, CA 92093, USA.
University of California San Diego · USScripps Mercy Hospital · US

Funding

Training In Cardiovascular Physiology & PharmacologyT32HL007444 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Ju Chen, Robert Scott Ross · 1985 to 2026
$11.1M
UCSD PRIDE Faculty Development Program in Cardiovascular SciencesR25HL145817 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI Robert Scott Ross, Joann Trejo · 2019 to 2026
$3.3M
Comprehensive Assessment of Right Ventricular and Pulmonary Vascular Function via CT Imaging in Heart Failure PatientsK01HL143113 · NHLBI · UNIVERSITY OF CALIFORNIA, SAN DIEGO · PI CONTIJOCH, FRANCISCO J · 2018 to 2022
$872k
Replacement of Small Animal Echocardiographic InstrumentationS10OD010417 · OD · VETERANS MEDICAL RESEARCH FDN/SAN DIEGO · PI ROSS, ROBERT SCOTT · 2012 to 2012
$371k
NHLBI NIH HHS K01 HL143113NHLBI NIH HHS R25 HL145817NHLBI NIH HHS T32 HL007444NIH HHS S10 OD010417
6 · The paper itself

Abstract

aimsTo develop an automated method for bloodpool segmentation and imaging plane re-slicing of cardiac computed tomography (CT) via deep learning (DL) for clinical use in coronary artery disease (CAD) wall motion assessment and reproducible longitudinal imaging. METHODS AND

resultsOne hundred patients who underwent clinically indicated cardiac CT scans with manually segmented left ventricle (LV) and left atrial (LA) chambers were used for training. For each patient, long-axis (LAX) and short-axis planes were manually defined by an imaging expert. A DL model was trained to predict bloodpool segmentations and imaging planes. Deep learning bloodpool segmentations showed close agreement with manual LV [median Dice: 0.91, Hausdorff distance (HD): 6.18 mm] and LA (Dice: 0.93, HD: 7.35 mm) segmentations and a strong correlation with manual ejection fraction (Pearson

conclusionA volumetric, DL approach provides multiple chamber segmentations and can re-slice the imaging volume along standardized cardiac imaging planes for reproducible wall motion abnormality and functional assessment.

Indexed as

Computed tomographyDeep learningLeft atriumLeft ventricleWall motion abnormality

Identifiers

PMID34223176
PMCPMC8242184
OpenAlexW3138268379

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.