Evidence map›Paper›PMID 34223141›Full record

ArticleJAC-antimicrobial resistance2021

Prevalence of ESBL-producing

Ioana D Olaru, Rashida A Ferrand, Mutsawashe Chisenga, Shunmay Yeung, Bruce Macrae, Prosper Chonzi, Richard A Stabler, Heidi Hopkins, David Mabey, Kudzai P E Masunda and 1 more

Open access · goldAbstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
3.8field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 21 citations in OpenAlex.

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  6. Frontiers in cellular and infection microbiology · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 3 institutions in 2 countries.

Ioana D OlaruLondon School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.ORCID https://orcid.org/0000-0003-3392-9257
Rashida A FerrandLondon School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Mutsawashe ChisengaBiomedical Research and Training Institute, 10 Seagrave Road, Harare, Zimbabwe.
Shunmay YeungLondon School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.ORCID https://orcid.org/0000-0002-0997-0850
Bruce MacraeClinical Microbiology, University College London Hospitals NHS Foundation Trust, 235 Euston Road, Bloomsbury, London NW1 2BU, UK.
Prosper ChonziDepartment of Health, Harare City Council, Rowan Martin Building, 1 Pennefather Avenue, Harare, Zimbabwe.
Richard A StablerLondon School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Heidi HopkinsLondon School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
David MabeyLondon School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
Kudzai P E MasundaDepartment of Health, Harare City Council, Rowan Martin Building, 1 Pennefather Avenue, Harare, Zimbabwe.
Katharina KranzerLondon School of Hygiene and Tropical Medicine, Keppel Street, London WC1E 7HT, UK.
University of London · GBBiomedical Research and Training Institute · ZWUniversity College London Hospitals NHS Foundation Trust · GB

Funding

Wellcome Trust 206316/Z/17/Z
6 · The paper itself

Abstract

backgroundPeople living with HIV may be at increased risk for infections with resistant organisms. Infections with ESBL-producing organisms are of particular concern because they limit treatment options for severe Gram-negative infections in low-resource settings.

objectivesTo investigate the association between HIV status and urinary tract infections (UTIs) with ESBL-producing PATIENTS AND

methodsCross-sectional study enrolling adults presenting with UTI symptoms to primary care clinics in Harare, Zimbabwe. Demographic and clinical data were collected during interviews and a urine sample was collected for culture from each participant. Antimicrobial susceptibility testing was performed according to EUCAST recommendations.

resultsOf the 1164 who were enrolled into the study, 783 (64%) were female and 387 (33%) were HIV infected. The median age was 35.8 years. Urine cultures were positive in 338 (29.0%) participants, and the majority of bacterial isolates were

conclusionsThis study found an association between HIV and ESBL-producing

Identifiers

PMID34223141
PMCPMC8242135
OpenAlexW3180850954

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.