Evidence map›Paper›PMID 34223104›Full record

ArticleJAC-antimicrobial resistance2021

Dissemination mechanisms of NDM genes in hospitalized patients.

Yuting Zhai, Shinyoung Lee, Lin Teng, Zhengxin Ma, Nicole B Hilliard, Robert J May, Scott A Brown, Fahong Yu, Kathryn E Desear, Kartik Cherabuddi and 4 more

Open access · goldAbstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed
0.9field-weighted citation impact, top 32% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 16 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

14 authors at 2 institutions in 1 country.

Yuting ZhaiEmerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
Shinyoung LeeEmerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
Lin TengEmerging Pathogens Institute, University of Florida, Gainesville, FL, USA.ORCID https://orcid.org/0000-0002-6871-0338
Zhengxin MaEmerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
Nicole B HilliardInfection Control, University of Florida Health/Shands Hospital, Gainesville, FL, USA.
Robert J MayInfection Control, University of Florida Health/Shands Hospital, Gainesville, FL, USA.
Scott A BrownInfection Control, University of Florida Health/Shands Hospital, Gainesville, FL, USA.
Fahong YuICBR, University of Florida, Gainesville, FL, USA.
Kathryn E DesearDepartment of Pharmacy, University of Florida Health/Shands Hospital, Gainesville, FL, USA.
Kartik CherabuddiDivision of Infectious Diseases and Global Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.ORCID https://orcid.org/0000-0001-7390-9053
Kenneth H RandDivision of Infectious Diseases and Global Medicine, College of Medicine, University of Florida, Gainesville, FL, USA.
J Glenn MorrisEmerging Pathogens Institute, University of Florida, Gainesville, FL, USA.ORCID https://orcid.org/0000-0001-9347-1984
Nicole M IovineInfection Control, University of Florida Health/Shands Hospital, Gainesville, FL, USA.
KwangCheol C JeongEmerging Pathogens Institute, University of Florida, Gainesville, FL, USA.
University of Florida · USUF Health Shands Hospital · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundNDM-producing Enterobacteriaceae are a major clinical concern worldwide. We characterized NDM-positive pathogens isolated from patients and assessed the dissemination patterns of the

methodsEleven NDM-positive Enterobacteriaceae (three

results

conclusionsMultiple transmission patterns were identified in hospitalized patients, including dissemination of clonal bacterial strains carrying resistance genes and horizontal transfer of resistance genes among divergent bacterial strains. Controlling spread of NDM is complex: while attention to standard infection control practices is critically important, this needs to be matched by aggressive efforts to limit unnecessary antimicrobial use, to minimize the selection for and risk of transfer of 'high mobility' resistance genes among Enterobacteriaceae.

Identifiers

PMID34223104
PMCPMC8210240
OpenAlexW3144774521

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.