Evidence map›Paper›PMID 34223090›Full record

ArticleJAC-antimicrobial resistance2021

PRO: Carbapenems should be used for ALL infections caused by ceftriaxone-resistant Enterobacterales.

David L Paterson, Burcu Isler, Patrick N A Harris

Open access · goldAbstract readComment
In one paragraph

Article in JAC-antimicrobial resistance, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.0field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Prevalence of New Delhi Metallo-β-lactamase (blaMolecular biology reports · 2025
    Article
  2. Article
  3. Article
  4. The neglected importance of high-endemic ESBL sites.JAC-antimicrobial resistance · 2022
    Article
  5. Article
  6. Antimicrobial Challenge in Acute Care Surgery.Antibiotics (Basel, Switzerland) · 2022
    Review
  7. Review
  8. Review
  9. Review
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

David L PatersonUniversity of Queensland Centre for Clinical Research (UQCCR), RBWH Campus, Brisbane, Australia.
Burcu IslerUniversity of Queensland Centre for Clinical Research (UQCCR), RBWH Campus, Brisbane, Australia.ORCID 0000-0003-1362-2434
Patrick N A HarrisUniversity of Queensland Centre for Clinical Research (UQCCR), RBWH Campus, Brisbane, Australia.ORCID 0000-0002-2895-0345
The University of Queensland · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Ceftriaxone resistance in the Enterobacterales is typically the result of production of ESBLs or AmpC β-lactamases. The genes encoding these enzymes are often co-located with other antibiotic resistance genes leading to resistance to aminoglycosides, quinolones and trimethoprim/sulfamethoxazole. Carbapenems are stable to ESBLs and AmpC giving them reliable

Identifiers

PMID34223090
PMCPMC8210194
OpenAlexW3130100465

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.