Evidence map›Paper›PMID 34222988›Full record

ArticleJAC-antimicrobial resistance2020

Multicentre study of the

Adela Alvarez-Buylla, Mike Allen, Dan Betts, Sean Bennett, Irene Monahan, Tim Planche, INVICTUS study group

Abstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Adela Alvarez-BuyllaMSD Ltd, Hoddesdon, Hertfordshire, UK.
Mike AllenMSD Ltd, Hoddesdon, Hertfordshire, UK.
Dan BettsMSD Ltd, Hoddesdon, Hertfordshire, UK.
Sean BennettMSD Ltd, Hoddesdon, Hertfordshire, UK.
Irene MonahanSt George's University Hospitals NHS Foundation Trust, London, UK.
Tim PlancheSt George's University Hospitals NHS Foundation Trust, London, UK.
INVICTUS study group

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo evaluate the

methodsThe

resultsOverall, 1326 clinical isolates from 14 centres in the UK were tested. The majority of the isolates were collected from non-cystic fibrosis (non-CF) patients (

conclusionsThe data presented here support the need to investigate the place of ceftolozane/tazobactam as a treatment option in the management of pseudomonal infections, particularly in patients with CF. The results highlight the importance of routine testing of new antibacterial agents and of making the data available to clinicians to make appropriate and informed treatment choices.

Identifiers

PMID34222988
PMCPMC8209992

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.