Evidence map›Paper›PMID 34222986›Full record

ArticleJAC-antimicrobial resistance2020

Routine laboratory surveillance of antimicrobial resistance in community-acquired urinary tract infections adequately informs prescribing policy in England.

Vicky Watts, Benjamin Brown, Maria Ahmed, André Charlett, Carolyn Chew-Graham, Paul Cleary, Valerie Decraene, Kirsty Dodgson, Ryan George, Susan Hopkins and 2 more

Abstract read
In one paragraph

Article in JAC-antimicrobial resistance, 2020. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed, 2 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 2 syntheses or guidelines pooled it.

  1. Pooled it
  2. Pooled it
  3. Review
  4. Observational
  5. Article
  6. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Vicky WattsField Service North West, National Infection Service, Public Health England, Liverpool, UK.
Benjamin BrownCentre for Primary Care, Division of Population Health, School of Health Sciences, Faculty of Biology, Medicine and Health, University of Manchester, Manchester, UK.
Maria AhmedManchester Medical, Moss Side Health Centre, Manchester, UK.
André CharlettStatistics Unit, Data and Analytical Sciences, National Infection Service, Public Health England, London, UK.
Carolyn Chew-GrahamSchool of Primary, Community and Social Care, Keele University, Keele, Newcastle-under-Lyme, UK.
Paul ClearyField Service North West, National Infection Service, Public Health England, Liverpool, UK.
Valerie DecraeneField Service North West, National Infection Service, Public Health England, Liverpool, UK.
Kirsty DodgsonManchester University NHS Foundation Trust, Manchester, UK.
Ryan GeorgeManchester University NHS Foundation Trust, Manchester, UK.
Susan HopkinsHCAI & AMR Division, National Infection Service, Public Health England, London, UK.
Aneez EsmailNIHR School for Primary Care Research, Manchester Academic Health Science Centre, University of Manchester, Manchester, UK.
William WelfareHealth Protection Team, Public Health England North West, Manchester, UK.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesTo assess whether resistance estimates obtained from sentinel surveillance for antimicrobial resistance (AMR) in community-acquired urinary tract infections (UTIs) differ from routinely collected laboratory community UTI data.

methodsAll patients aged ≥18

resultsSentinel practices submitted 740 eligible specimens. The specimen submission rate had increased by 28 specimens per 1000 population per year (95% CI 21-35). Uropathogens were isolated from 23% (169/740) of specimens; 67% were

conclusionsRoutine laboratory data resulted in a small overestimation in resistance (although the difference was not statistically significant) and our findings suggest that it provides an adequate estimate of non-susceptibility to key antimicrobials in community-acquired UTIs in England. This study does not support the need for ongoing local sentinel surveillance.

Identifiers

PMID34222986
PMCPMC8210191

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.