Evidence map›Paper›PMID 34222866›Full record

ArticleBrain communications2021

Axonal loss in major sensorimotor tracts is associated with impaired motor performance in minimally disabled multiple sclerosis patients.

Myrte Strik, L Eduardo Cofré Lizama, Camille J Shanahan, Anneke van der Walt, Frederique M C Boonstra, Rebecca Glarin, Trevor J Kilpatrick, Jeroen J G Geurts, Jon O Cleary, Menno M Schoonheim and 2 more

Open access · goldAbstract read
In one paragraph

Article in Brain communications, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
2.3field-weighted citation impact, top 12% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 21 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors at 5 institutions in 3 countries.

Myrte StrikDepartment of Medicine and Radiology, University of Melbourne, Parkville 3010, Australia.ORCID https://orcid.org/0000-0001-8995-9899
L Eduardo Cofré LizamaDepartment of Medicine and Radiology, University of Melbourne, Parkville 3010, Australia.
Camille J ShanahanDepartment of Medicine and Radiology, University of Melbourne, Parkville 3010, Australia.
Anneke van der WaltDepartment of Neurosciences, Central Clinical School, Monash University, Melbourne 3004, Australia.
Frederique M C BoonstraDepartment of Neurosciences, Central Clinical School, Monash University, Melbourne 3004, Australia.
Rebecca GlarinDepartment of Medicine and Radiology, University of Melbourne, Parkville 3010, Australia.
Trevor J KilpatrickFlorey Institute of Neuroscience and Mental Health, Parkville 3052, Australia.
Jeroen J G GeurtsDepartment of Anatomy and Neurosciences, MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam 1081 HZ, the Netherlands.
Jon O ClearyDepartment of Radiology, Guy's and St. Thomas' NHS Foundation Trust, London SE1 7EH, UK.
Menno M SchoonheimDepartment of Anatomy and Neurosciences, MS Center Amsterdam, Amsterdam Neuroscience, Amsterdam UMC, Vrije Universiteit Amsterdam, Amsterdam 1081 HZ, the Netherlands.ORCID https://orcid.org/0000-0002-2504-6959
Mary P GaleaDepartment of Medicine and Radiology, University of Melbourne, Parkville 3010, Australia.
Scott C KolbeDepartment of Medicine and Radiology, University of Melbourne, Parkville 3010, Australia.
The University of Melbourne · AUAmsterdam Neuroscience · NLMonash University · AUGuy's and St Thomas' NHS Foundation Trust · GBThe Royal Melbourne Hospital · AU

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Multiple sclerosis is a neuroinflammatory disease of the CNS that is associated with significant irreversible neuro-axonal loss, leading to permanent disability. There is thus an urgent need for

Indexed as

axonal degenerationdiffusion-weighted imagingmotor disabilitymultiple sclerosisultra-high field imaging

Identifiers

PMID34222866
PMCPMC8244644
OpenAlexW3138917127

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.