Evidence map›Paper›PMID 34222812›Full record

ArticleNorthern clinics of Istanbul2021

Association of blood groups on the risk of COVID-19 infection, morbidity, and mortality.

Meltem Sertbas, Volkan Kizilay, Selma Dagci, Pinar Eker, Zeynep Yazici, Ebru Elci Solak, Serkan Elarslan, Nurettin Yiyit, Yasar Sertbas, Kamil Ozdil

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Article in Northern clinics of Istanbul, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

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5 · Who and what money

Authors and funding

10 authors.

Meltem SertbasDepartment of Internal Medicine, Health Sciences University Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Turkey.
Volkan KizilayDepartment of Gastroenterology, Health Sciences University Umraniye Training and Research Hospital, Istanbul, Turkey.
Selma DagciDepartment of Gastroenterology, Health Sciences University Umraniye Training and Research Hospital, Istanbul, Turkey.
Pinar EkerDepartment of Gastroenterology, Health Sciences University Umraniye Training and Research Hospital, Istanbul, Turkey.
Zeynep YaziciDepartment of Cardiology, Health Sciences University Siyami Ersek Training and Research Hospital, Istanbul, Turkey.
Ebru Elci SolakDepartment of Cardiology, Health Sciences University Siyami Ersek Training and Research Hospital, Istanbul, Turkey.
Serkan ElarslanDepartment of Internal Medicine, Health Sciences University Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Turkey.
Nurettin YiyitDepartment of Thoracic Surgery, Health Sciences University Sehit Prof. Ilhan Varank Training and Research Hospital, Istanbul, Turkey.
Yasar SertbasDepartment of Internal Medicine, Health Sciences University Fatih Sultan Mehmet Training and Research Hospital, Istanbul, Turkey.
Kamil OzdilDepartment of Gastroenterology, Health Sciences University Umraniye Training and Research Hospital, Istanbul, Turkey.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectiveWe aimed to compare the effects of blood groups and Rh factor on the development of coronavirus-19 disease (COVID-19) with all aspects such as clinical course, inflammatory parameters, and organ-specific biochemical parameters with a significant number of patients.

methodsThis multicenter study was carried out retrospectively on 3551 patients hospitalized with the diagnosis of COVID-19 and whose blood groups were recorded during the time of hospitalization. As control groups, 22133 individuals' medical data who were admitted to the blood bank affiliated with our hospitals during the last year was used. The differences between the blood groups and clinical characteristics were analyzed.

resultsOf the 3551 patients, A Rh (+) blood group was found to be in a higher ratio in the case group than controls, with increased risk to be infected (case: 41.3% vs. control: 38.8%), (OR 1.113; 95% CI: 1.036-1.197; p=0.003). Meanwhile O Rh (+) blood group ratios were significantly lower in the case group than in the control group (case: 26% vs. control: 28.3%) (OR 0.862; 95% CI: 0.823-0.966; p=0.005). There was no significant difference between blood groups in terms of admission to the intensive care units and mortality, it was observed that patients with AB Rh (+) blood group have a greater risk for intubation than others (OR: 1.467; 95% CI: 1.040-2.071; p=0.028).

conclusionWe demonstrated that people with blood group A Rh (+) more susceptible to COVID-19, whereas blood group 0 Rh (+) have a protective effect against the infection. Once a person has been infected with severe acute respiratory syndrome coronavirus 2, we should be mindful that patients with blood group AB Rh (+) would be prone to intubation more than other blood groups.

Indexed as

Blood groupscoronavirus-19 diseasesevere acute respiratory syndrome coronavirus 2

Identifiers

PMID34222812
PMCPMC8240239

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.