ArticleNorthern clinics of Istanbul2021
Evaluation of quality of life and its associations with clinical parameters in pediatric patients with familial Mediterranean fever.
Article in Northern clinics of Istanbul, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT05980780 (Video Developed for Children With Familial Mediterranean Fever The Effect of Game on Disease Management and Quality of Life), which is not on this map. Cited by 8 papers.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Video Developed for Children With Familial Mediterranean Fever The Effect of Game on Disease Management and Quality of Life
Who cites it
8 citing papers in PubMed.
- Sleep Quality and Depressive Symptoms in Clinically Stable Pediatric Familial Mediterranean Fever: Associations with Disease Severity and Developmental Factors.Children (Basel, Switzerland) · 2026Article
- Colchicine-Tolerant vs. Resistant Familial Mediterranean Fever: Comparative Analysis of Clinical, Psychosocial Characteristics and Quality of Life.Journal of clinical medicine · 2026Article
- Practical considerations for monitoring patients with familial Mediterranean fever: review of evidence and expert opinion.Frontiers in immunology · 2026Review
- The effects of self-efficacy in managing the disease and disease adaptation levels of Familial Mediterranean Fever (fmf) patients on satisfaction with life: a web-based cross-sectional study.Orphanet journal of rare diseases · 2025Observational
- The Turkish Pain Catastrophizing Scale-Child in Adolescents with Familial Mediterranean Fever: A Psychometric Analysis.Archives of rheumatology · 2025Article
- The effect of education given to Turkish adolescents with Familial Mediterranean fever on anxiety, depression, and quality of life.European journal of pediatrics · 2023Article
- Ureterocystoplasty in Boys with Valve Bladder Syndrome-Is This Method Still up to Date?Children (Basel, Switzerland) · 2023Article
- Real-Life Indications of Interleukin-1 Blocking Agents in Hereditary Recurrent Fevers: Data From the JIRcohort and a Literature Review.Frontiers in immunology · 2021Review
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5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
objectiveA favorable quality of life (QoL) is important in children with chronic disease, and it reflects successful disease management. The aim of our study was to evaluate QoL and its association with clinical parameters in pediatric patients with familial Mediterranean fever (FMF).
methodsThe Kinder Lebensqualität Fragebogen (KINDL
resultsThe KINDL QoL scores of the FMF patients were significantly lower than their healthy peers. The physical and emotional well-being KINDL QoL scores of the FMF children were significantly lower than their healthy peers (p=0.017 and p=0.020, respectively). In the evaluation of the KINDL QoL scores between the kiddy and kid groups, only the self-esteem score was higher in the kiddy group (p=0.004), and the school functioning scores were higher in the kid group (p=0.002). The scores in the physical well-being and disease module had significant differences between patients who were adherent and those who were non-adherent to colchicine therapy (p=0.042 and p=0.047, respectively). The scores in the physical well-being and disease module were significantly higher in patients with fewer attacks than those who had many attacks per year (p=0.004 and p=0.014, respectively).
conclusionThis study suggests that FMF patients have significantly impaired QoL. The irregular use of colchicine and more frequent attacks affect QoL even more. A QoL assessment with multidisciplinary follow-up and control of the disease activity are essential, and if necessary, individualized support should be given to patients.
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