Evidence map›Paper›PMID 34222538›Full record

ArticleInternational journal of advances in science, engineering and technology2019

META-ANALYSIS OF DOLPHIN AND HUMAN PERIPHERAL BLOOD MONONUCLEAR CELLS REVEALS INFLAMMATORY SIGNATURES ASSOCIATED WITH EXPOSURE TO HIGH LEVELS OF PERFLUOROALKYL SUBSTANCES.

Bethany J Wolf, Diane L Kamen, Patricia Fair, Gary Hardiman

Open access · greenAbstract read
In one paragraph

Article in International journal of advances in science, engineering and technology, 2019. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact, top 77% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed, 0 citations in OpenAlex.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Bethany J WolfDepartment of Public Health Sciences, Medical University of South Carolina (MUSC), Charleston, SC.
Diane L KamenDepartment of Medicine, MUSC. USA.
Patricia FairDepartment of Public Health Sciences, Medical University of South Carolina (MUSC), Charleston, SC.
Gary HardimanDepartment of Medicine, MUSC. USA, School of Biological Sciences & Institute for Global Food Security, Queens University Belfast, Belfast, UK.
Medical University of South Carolina · US

Funding

South Carolina Clinical & Translational Research Institute (SCTR)UL1TR001450 · NCATS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI BRADY, KATHLEEN T., FLUME, PATRICK A · 2015 to 2024
$41.1M
Resource CoreP30AR072582 · NIAMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI JAMES C OATES · 2017 to 2026
$8.5M
Sphingosine Kinase in Systemic Sclerosis (Scleroderma)P60AR049459 · NIAMS · MEDICAL UNIVERSITY OF SOUTH CAROLINA · PI SILVER, RICHARD M. · 2003 to 2007
$6.0M
NCATS NIH HHS UL1 TR001450NIAMS NIH HHS P30 AR072582NIAMS NIH HHS P60 AR049459
6 · The paper itself

Abstract

Currently a fundamental gap exists on how persistent organic pollutants affect humans especially those who consume high levels of seafood from contaminated coastal waters. There is an urgent need to better understand effects of these contaminants on human health in coastal communities. Elevated contaminant levels in coastal seafood will give rise to increased contaminant burdens in humans who consume coastal seafood and given the toxicity of these contaminants increase risk for immune system disorders. In this paper we describe how we assessed the effects of contaminant exposures using high-throughput RNA sequencing (RNA-seq) in peripheral blood mononuclear cells from two species, dolphins and humans. This paper presents an integrated systems biology approach to understand the adverse effects of one of these CECs PFAS on both species.

Indexed as

One HealthPBDEsPBMCPFASsSystems Biology

Identifiers

PMID34222538
PMCPMC8248928
OpenAlexW3180719807

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.