Evidence map›Paper›PMID 34222487›Full record

ArticleBioMed research international2021

Involvement of GABA

Jéssica C Andrade, Álefe B Monteiro, Humberto H N Andrade, Thallita K S N Gonzaga, Pablo R Silva, Danielle N Alves, Ricardo D Castro, Mayara S Maia, Marcus T Scotti, Damião P Sousa and 1 more

Open access · hybridAbstract read
In one paragraph

Article in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.7field-weighted citation impact, top 18% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 18 citations in OpenAlex.

  1. Article
  2. Article
  3. Article
  4. Review
  5. Effects of Five Coumarins and Standardized Extracts fromPharmaceuticals (Basel, Switzerland) · 2023
    Article
  6. Anxiolytic-Pharmaceuticals (Basel, Switzerland) · 2023
    Article
  7. Article
  8. Phenolics as GABAMolecules (Basel, Switzerland) · 2022
    Review
  9. Activation ofInternational journal of molecular sciences · 2021
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 1 institution in 1 country.

Jéssica C AndradePsychopharmacology Laboratory, Institute of Drugs and Medicines Research, Federal University of Paraíba, Campus I, 58051-085, Via Ipê Amarelo/SN, João Pessoa, Paraíba, Brazil.ORCID https://orcid.org/0000-0003-4935-6625
Álefe B MonteiroPsychopharmacology Laboratory, Institute of Drugs and Medicines Research, Federal University of Paraíba, Campus I, 58051-085, Via Ipê Amarelo/SN, João Pessoa, Paraíba, Brazil.ORCID https://orcid.org/0000-0003-2916-0246
Humberto H N AndradePsychopharmacology Laboratory, Institute of Drugs and Medicines Research, Federal University of Paraíba, Campus I, 58051-085, Via Ipê Amarelo/SN, João Pessoa, Paraíba, Brazil.ORCID https://orcid.org/0000-0003-0377-7985
Thallita K S N GonzagaPsychopharmacology Laboratory, Institute of Drugs and Medicines Research, Federal University of Paraíba, Campus I, 58051-085, Via Ipê Amarelo/SN, João Pessoa, Paraíba, Brazil.ORCID https://orcid.org/0000-0002-8996-760X
Pablo R SilvaPsychopharmacology Laboratory, Institute of Drugs and Medicines Research, Federal University of Paraíba, Campus I, 58051-085, Via Ipê Amarelo/SN, João Pessoa, Paraíba, Brazil.ORCID https://orcid.org/0000-0001-8354-3198
Danielle N AlvesDepartment of Clinic and Social Dentistry, Center for Health Sciences, Federal University of Paraiba, Campus I, João Pessoa, PB, Brazil.ORCID https://orcid.org/0000-0002-3072-0928
Ricardo D CastroDepartment of Clinic and Social Dentistry, Center for Health Sciences, Federal University of Paraiba, Campus I, João Pessoa, PB, Brazil.ORCID https://orcid.org/0000-0001-7986-7376
Mayara S MaiaCheminformatics Laboratory, Institute of Drugs and Medicines Research, Federal University of Paraíba, Campus I, 58051-900, Via Ipê Amarelo/SN, João Pessoa, Paraíba, Brazil.ORCID https://orcid.org/0000-0002-5306-8362
Marcus T ScottiCheminformatics Laboratory, Institute of Drugs and Medicines Research, Federal University of Paraíba, Campus I, 58051-900, Via Ipê Amarelo/SN, João Pessoa, Paraíba, Brazil.ORCID https://orcid.org/0000-0003-4863-8057
Damião P SousaPharmaceutical Chemistry Laboratory, Institute of Drugs and Medicines Research, Federal University of Paraíba, João Pessoa, Brazil.ORCID https://orcid.org/0000-0002-7180-4896
Reinaldo N AlmeidaPsychopharmacology Laboratory, Institute of Drugs and Medicines Research, Federal University of Paraíba, Campus I, 58051-085, Via Ipê Amarelo/SN, João Pessoa, Paraíba, Brazil.ORCID https://orcid.org/0000-0003-4430-8202
Universidade Federal da Paraíba · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hydroxycitronellal (HC) is a monoterpene present in essential oils of aromatic plants of different species, obtained from semisynthesis of citronellal, and is widely used as a fragrance in cosmetics. The objective of this work was to evaluate the possible anxiolytic-like activity of HC and its possible mechanism of action using

Indexed as

AnimalsAnti-Anxiety AgentsAnxietyBehavior, AnimalComputer SimulationHydrogen BondingHypnotics and SedativesLength of StayMaleMaze LearningMiceMolecular Docking SimulationMotor ActivityReceptors, GABA-ATerpenesTreatment OutcomeAnti-Anxiety AgentshydroxycitronellalHypnotics and SedativesReceptors, GABA-ATerpenes

Identifiers

PMID34222487
PMCPMC8225436
OpenAlexW3167815845

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.