Trial reportBioMed research international2021
The Effects of Lavender and Citrus aurantium on Anxiety and Agitation of the Conscious Patients in Intensive Care Units: A Parallel Randomized Placebo-Controlled Trial.
Trial report in BioMed research international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
11 citing papers in PubMed, 1 synthesis or guideline pooled it, 34 citations in OpenAlex.
- Effects of aromatherapy on objective physiological outcomes in adult ICU patients: a systematic review.Frontiers in medicine · 2026Pooled it
- Effect of Citrus Aurantium L. on pain and blood pressure in patients undergoing hand reconstructive surgery.Pain management · 2025Trial
- A Comparative Assessment of Three Different Behavior Modification Techniques Using Physiological and Psychological Parameters: AnInternational journal of clinical pediatric dentistry · 2026Article
- Effect of Lavender Essential Oil-based Aromatherapy on Anxiety: An Overview of Results of Recent Randomized Controlled Trials.Current pharmaceutical design · 2026Review
- Review
- Integrative and complementary practices in Intensive Care Units: An integrative review.Heliyon · 2024Review
- Anxiety-Reducing Effects of Lavender Essential Oil Inhalation: A Systematic Review.Healthcare (Basel, Switzerland) · 2023Review
- Review
- Stigma and Efficacy of Zhizhu Kuanzhong Capsules Versus Doxepin in the Treatment of Refractory Functional Dyspepsia: A Randomized Controlled Trial.Journal of neurogastroenterology and motility · 2023Article
- The Effects of Essential Oils on the Nervous System: A Scoping Review.Molecules (Basel, Switzerland) · 2023Article
- A Narrative Review of the Effects of Citrus Peels and Extracts on Human Brain Health and Metabolism.Nutrients · 2022Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors at 1 institution in 1 country.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundConscious patients admitted to intensive care units (ICU) suffer from anxiety and agitation for various reasons, which can affect their recovery processes.
aimsTo compare the effects of lavender and Citrus aurantium essential oils on anxiety and agitation of conscious patients admitted to ICUs.
designA randomized parallel placebo-controlled trial.
methodsOne hundred and fifty conscious patients admitted to ICUs were selected by convenience sampling and were randomly divided into three groups, groups of lavender aromatherapy and Citrus aurantium aromatherapy, in addition to the routine care and inhalation of five drops of lavender or Citrus aurantium essential oils for 30 minutes. The placebo group, in addition to routine care, was provided with 5 drops of normal saline for 30 minutes. Anxiety was assessed with the state subscale of State-Trait Anxiety Inventory, and agitation was examined with Richmond Agitation-Sedation Scale before, immediately, one hour, and three hours after the intervention.
resultsAll three groups suffered from relatively severe state anxiety before the intervention. The level of anxiety in the lavender and Citrus aurantium groups was significantly lower than that of the placebo group immediately and three hours after the intervention (
conclusionThe results of the present study showed the positive effects of lavender aromatherapy and Citrus aurantium aromatherapy on reducing the anxiety of patients admitted to ICUs.
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Registered trials
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