Evidence map›Paper›PMID 34222419›Full record

ReviewWorld journal of clinical cases2021

Roles of vitamin A in the regulation of fatty acid synthesis.

Fu-Chen Yang, Feng Xu, Tian-Nan Wang, Guo-Xun Chen

Open access · diamondAbstract readReview
In one paragraph

Review in World journal of clinical cases, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.

0numbers the graph read from it
0cells of the map it votes in
16citing papers in PubMed
0.7field-weighted citation impact, top 31% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

16 citing papers in PubMed, 19 citations in OpenAlex.

  1. Article
  2. Article
  3. The role and mechanisms of vitamin A in suppressing hepatic stellate cell activation.Apoptosis : an international journal on programmed cell death · 2026
    Article
  4. Review
  5. Article
  6. Article
  7. Review
  8. Review
  9. The Connection Between Cellular Metabolism and Retinal Disease.Advances in experimental medicine and biology · 2025
    Review
  10. Article
  11. Article
  12. Review
  13. Article
  14. Article
  15. Review
  16. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors at 1 institution in 1 country.

Fu-Chen YangFood College, Jiangsu Food and Pharmaceutical College, Huaian 223003, Jiangsu Province, China.
Feng XuDepartment of Urology, The First Affiliated Hospital of Zhengzhou University, Zhengzhou 450052, Henan Province, China.
Tian-Nan WangDepartment of Nutrition, The University of Tennessee, Knoxville, TN 37909, United States.
Guo-Xun ChenDepartment of Nutrition, The University of Tennessee, Knoxville, TN 37909, United States. gchen6@utk.edu.
First Affiliated Hospital of Zhengzhou University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Dietary macronutrients and micronutrients play important roles in human health. On the other hand, the excessive energy derived from food is stored in the form of triacylglycerol. A variety of dietary and hormonal factors affect this process through the regulation of the activities and expression levels of those key player enzymes involved in fatty acid biosynthesis such as acetyl-CoA carboxylase, fatty acid synthase, fatty acid elongases, and desaturases. As a micronutrient, vitamin A is essential for the health of humans. Recently, vitamin A has been shown to play a role in the regulation of glucose and lipid metabolism. This review summarizes recent research progresses about the roles of vitamin A in fatty acid synthesis. It focuses on the effects of vitamin A on the activities and expression levels of mRNA and proteins of key enzymes for fatty acid synthesis

Indexed as

Acetyl-CoA carboxylaseFatty acid elongaseFatty acid synthaseFatty acid synthesisStearoyl-CoA desaturaseVitamin A

Identifiers

PMID34222419
PMCPMC8223857
OpenAlexW3169054940

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.