Evidence map›Paper›PMID 34222393›Full record

ArticleFrontiers in veterinary science2021

Milk Macrophage Function in Bovine Leukemia Virus-Infected Dairy Cows.

Ewerton de Souza Lima, Maiara Garcia Blagitz, Camila Freitas Batista, Alexandre José Alves, Artur Cezar de Carvalho Fernandes, Eduardo Milton Ramos Sanchez, Hugo Frias Torres, Soraia Araújo Diniz, Marcos Xavier Silva, Alice Maria Melville Paiva Della Libera and 1 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in veterinary science, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
0.5field-weighted citation impact, top 40% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

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  7. BLV-miR-B1-5p PromotesAnimals : an open access journal from MDPI · 2023
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors at 4 institutions in 2 countries.

Ewerton de Souza LimaNúcleo Aplicado à Produção e Sanidade da Glândula Mamária, Departamento de Medicina Veterinária, Centro de Ciências Agrárias, Universidade Federal da Paraíba, Areia, Brazil.
Maiara Garcia BlagitzVeterinary Clinical Immunology Research Group, Departamento de Clínica Médica, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, Brazil.
Camila Freitas BatistaVeterinary Clinical Immunology Research Group, Departamento de Clínica Médica, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, Brazil.
Alexandre José AlvesNúcleo Aplicado à Produção e Sanidade da Glândula Mamária, Departamento de Medicina Veterinária, Centro de Ciências Agrárias, Universidade Federal da Paraíba, Areia, Brazil.
Artur Cezar de Carvalho FernandesNúcleo Aplicado à Produção e Sanidade da Glândula Mamária, Departamento de Medicina Veterinária, Centro de Ciências Agrárias, Universidade Federal da Paraíba, Areia, Brazil.
Eduardo Milton Ramos SanchezDepartment of Public Health, School of Health Sciences, National University Toribio Rodriguez de Mendonza of Amazonas, Chachapoyas, Peru.
Hugo Frias TorresParasitic and Infectious Diseases Laboratory, Animal Husbandry and Biotechnology Research Institute, Universidad Nacional Toribio Rodríguez de Mendoza, Chachapoyas, Peru.
Soraia Araújo DinizDepartamento de Medicina Veterinária Preventiva, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Marcos Xavier SilvaDepartamento de Medicina Veterinária Preventiva, Escola de Veterinária, Universidade Federal de Minas Gerais, Belo Horizonte, Brazil.
Alice Maria Melville Paiva Della LiberaVeterinary Clinical Immunology Research Group, Departamento de Clínica Médica, Faculdade de Medicina Veterinária e Zootecnia, Universidade de São Paulo, São Paulo, Brazil.
Fernando Nogueira de SouzaNúcleo Aplicado à Produção e Sanidade da Glândula Mamária, Departamento de Medicina Veterinária, Centro de Ciências Agrárias, Universidade Federal da Paraíba, Areia, Brazil.
Universidade de São Paulo · BRUniversidade Federal da Paraíba · BRNational University Toribio Rodríguez de Mendoza · PEUniversidade Federal de Minas Gerais · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The implications of bovine leukemia virus (BLV) on innate and adaptive immune responses have been widely investigated; however, the effects of BLV on mammary gland immunity require further investigation. The present study investigated the viability, phagocytic capacity, and intracellular production of reactive oxygen and nitrogen species (RONS) by macrophages in milk samples from dairy cows naturally infected with BLV with or without persistent lymphocytosis (PL). No effect of BLV infection in the overall number of macrophages per milliliter and in the percentage of viable macrophages among overall milk viable cells was found. Furthermore, BLV-infected dairy cows had a higher frequency of viable milk macrophages, while healthy animals had a tendency toward a higher percentage of apoptotic milk macrophages. The percentage of milk macrophages that phagocytosed

Indexed as

dairy cattledeltaretrovirusenzootic bovine leukosisimmune responsemastitis

Identifiers

PMID34222393
PMCPMC8245700
OpenAlexW3175728644

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.