Evidence map›Paper›PMID 34222376›Full record

ArticleFrontiers in cardiovascular medicine2021

Clinical and Functional Genetic Characterization of the Role of Cardiac Calcium Channel Variants in the Early Repolarization Syndrome.

Xiu Chen, Hector Barajas-Martínez, Hao Xia, Zhonghe Zhang, Ganxiao Chen, Bo Yang, Hong Jiang, Charles Antzelevitch, Dan Hu

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cardiovascular medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 8 papers.

0numbers the graph read from it
0cells of the map it votes in
8citing papers in PubMed
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

8 citing papers in PubMed, 13 citations in OpenAlex.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Primary Electrical Heart Disease-Principles of Pathophysiology and Genetics.International journal of molecular sciences · 2024
    Review
  6. Human Genetics of Cardiac Arrhythmias.Advances in experimental medicine and biology · 2024
    Review
  7. Functional identification of hot-spot mutations in cardiac calcium channel genes associated with the J wave syndromes.Philosophical transactions of the Royal Society of London. Series B, Biological sciences · 2023
    Article
  8. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 4 institutions in 2 countries.

Xiu ChenDepartment of Cardiology and Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, China.
Hector Barajas-MartínezLankenau Institute for Medical Research, Lankenau Heart Institute, Wynnewood, PA, United States.
Hao XiaDepartment of Cardiology and Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, China.
Zhonghe ZhangDepartment of Cardiology and Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, China.
Ganxiao ChenDepartment of Cardiology and Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, China.
Bo YangDepartment of Cardiology and Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, China.
Hong JiangDepartment of Cardiology and Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, China.
Charles AntzelevitchLankenau Institute for Medical Research, Lankenau Heart Institute, Wynnewood, PA, United States.
Dan HuDepartment of Cardiology and Cardiovascular Research Institute, Renmin Hospital of Wuhan University, Wuhan, China.
Renmin Hospital of Wuhan University · CNWuhan University · CNLankenau Heart Institute · USThomas Jefferson University · US

Funding

ELECTRICAL HETEROGENEITY AND CARDIAC ARRHYTHMIASR01HL047678 · NHLBI · MASONIC MEDICAL RESEARCH LABORATORY, INC · PI ANTZELEVITCH, CHARLES · 1993 to 2014
$5.7M
Development of a whole heart model of the J wave syndromes and novel approaches to pharmacologic management of associated life-threatening arrhythmiasR01HL152201 · NHLBI · LANKENAU INSTITUTE FOR MEDICAL RESEARCH · PI ANTZELEVITCH, CHARLES, DI DIEGO, JOSE M. · 2020 to 2023
$2.5M
Novel Approaches to Pharmacologic Management of Life-Threatening Arrhythmias Associated with the J Wave SyndromesR56HL138103 · NHLBI · LANKENAU INSTITUTE FOR MEDICAL RESEARCH · PI ANTZELEVITCH, CHARLES · 2018 to 2018
$413k
NHLBI NIH HHS R01 HL047678NHLBI NIH HHS R01 HL152201NHLBI NIH HHS R56 HL138103
6 · The paper itself

Abstract

PubMed holds no abstract for this paper.

Indexed as

calcium channelearly repolarization syndromegene mutationsudden cardiac deathtrafficking

Identifiers

PMID34222376
PMCPMC8249565
OpenAlexW3176784303

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.