Evidence map›Paper›PMID 34222341›Full record

ArticleFrontiers in molecular biosciences2021

LINC00174 Facilitates Cell Proliferation, Cell Migration and Tumor Growth of Osteosarcoma

Changjun Zheng, Ronghang Li, Shuang Zheng, Hongjuan Fang, Meng Xu, Lei Zhong

RetractedOpen access · goldAbstract readRetracted Publication
In one paragraph

Article in Frontiers in molecular biosciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It has been retracted, and should not be counted. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
1.5field-weighted citation impact, top 19% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 13 citations in OpenAlex.

  1. Article
  2. Review
  3. Article
  4. Article
  5. Review
  6. Article
  7. Article
4 · The record

Corrections and comments

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Changjun ZhengDepartment of Orthopedics, The Second Hospital of Jilin University, Changchun, China.
Ronghang LiDepartment of Orthopedics, The Second Hospital of Jilin University, Changchun, China.
Shuang ZhengDepartment of Orthopedics, The Second Hospital of Jilin University, Changchun, China.
Hongjuan FangDepartment of Electric Diagnostic, The Fourth Hospital of Jilin University, Changchun, China.
Meng XuDepartment of Orthopedics, The Second Hospital of Jilin University, Changchun, China.
Lei ZhongDepartment of Orthopedics, The Second Hospital of Jilin University, Changchun, China.
Second Affiliated Hospital of Jilin University · CNJilin University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Osteosarcoma (OS), a frequent malignant tumor which mainly occurs in the bone. The roles of long noncoding RNAs (lncRNAs) have been revealed in cancers, including OS. LncRNA long intergenic non-protein coding RNA (LINC00174) has been validated as an oncogene in several cancers. However, the role of LINC00174 in OS has not been explored. In our research, loss-of-function assays were conducted to explore the function of LINC00174 in OS cells. Then, we explored the downstream pathway of LINC00174 in OS cells. Bioinformatics, RNA pull-down and RIP experiments investigated the downstream mechanism of LINC00174 in OS cells. Finally,

Indexed as

LINC00174miR-378a-3pOSSSH2TGF-β/Smad

Identifiers

PMID34222341
PMCPMC8245779
OpenAlexW3174050672

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.