Evidence map›Paper›PMID 34222308›Full record

ArticleFrontiers in nutrition2021

Polyphenol-Rich

Ljiljana Stojković, Manja Zec, Maja Zivkovic, Maja Bundalo, Maja Bošković, Marija Glibetić, Aleksandra Stankovic

2 registry-linked trialsOpen access · goldAbstract read
In one paragraph

Article in Frontiers in nutrition, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 9 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed, 1 pooled it
2.0field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT02800967 naunknown statusnot on this map

Investigation of Beneficial Effects of Aronia Juice (Aronia Melanocarpa) and Dietary Polyphenols on the Activity of Thrombocytes as Well as Other Risk Factors Causing Cardio-vascular Diseases

TypeinterventionalSponsorUniversity of BelgradeRan2014 to 2017Enrolled84ConditionsHypertension, OverweightArmsPure Aronia juice, Aronia juice-based beverage, Placebo beverage
NCT05234203 nacompletednot on this mapstarted 2022, after this paper: background citation

The Impact of a Polyphenol-Rich Supplement on Epigenetic and Cellular Markers of Immune Age

TypeinterventionalSponsorBig Bold Health, PBCRan2022 to 2022Enrolled50ConditionsImmunity Disorders, Aging, InflammationArmsHTB Rejuvenate
3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 1 synthesis or guideline pooled it, 19 citations in OpenAlex.

  1. Impact of a Chokeberry (Nutrients · 2025
    Pooled it
  2. Review
  3. Review
  4. Functional Activities and Mechanisms ofCurrent issues in molecular biology · 2024
    Review
  5. Article
  6. Article
  7. Potential Benefits of Black Chokeberry (Molecules (Basel, Switzerland) · 2022
    Review
  8. Article
  9. Chokeberry (Nutrients · 2022
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 3 countries.

Ljiljana StojkovićLaboratory for Radiobiology and Molecular Genetics, Department of Health and Environmental Research, "Vinča" Institute of Nuclear Sciences-National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia.
Manja ZecCentre of Research Excellence in Nutrition and Metabolism, Institute for Medical Research-National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia.
Maja ZivkovicLaboratory for Radiobiology and Molecular Genetics, Department of Health and Environmental Research, "Vinča" Institute of Nuclear Sciences-National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia.
Maja BundaloLaboratory for Radiobiology and Molecular Genetics, Department of Health and Environmental Research, "Vinča" Institute of Nuclear Sciences-National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia.
Maja BoškovićLaboratory for Radiobiology and Molecular Genetics, Department of Health and Environmental Research, "Vinča" Institute of Nuclear Sciences-National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia.
Marija GlibetićCentre of Research Excellence in Nutrition and Metabolism, Institute for Medical Research-National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia.
Aleksandra StankovicLaboratory for Radiobiology and Molecular Genetics, Department of Health and Environmental Research, "Vinča" Institute of Nuclear Sciences-National Institute of the Republic of Serbia, University of Belgrade, Belgrade, Serbia.
University of Belgrade · RSUniversity of Arizona · US

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Cardiovascular disease (CVD) is associated with alterations in DNA methylation and polyunsaturated fatty acid (PUFA) profile, both modulated by dietary polyphenols. The present parallel, placebo-controlled study (part of the original clinical study registered as NCT02800967 at www.clinicaltrials.gov) aimed to determine the impact of 4-week daily consumption of polyphenol-rich

Indexed as

Aronia melanocarpacardiovascular riskLINE-1methylationperipheral blood leukocytespolyphenolspolyunsaturated fatty acids

Identifiers

PMID34222308
PMCPMC8247759
OpenAlexW3173367699

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.