Evidence map›Paper›PMID 34222271›Full record

ArticleFrontiers in medicine2021

Abnormal Coagulation Function of Patients With COVID-19 Is Significantly Related to Hypocalcemia and Severe Inflammation.

Xu Qi, Hui Kong, Wenqiu Ding, Chaojie Wu, Ningfei Ji, Mao Huang, Tiantian Li, Xinyu Wang, Jingli Wen, Wenjuan Wu and 5 more

Open access · goldAbstract read
In one paragraph

Article in Frontiers in medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 15% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 1 synthesis or guideline pooled it, 23 citations in OpenAlex.

  1. Pooled it
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  6. Review
  7. Review
  8. Predictors of COVID-19 severity among pregnant patients.Bosnian journal of basic medical sciences · 2022
    Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

15 authors at 3 institutions in 1 country.

Xu QiDepartment of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Hui KongDepartment of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Wenqiu DingDepartment of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Chaojie WuDepartment of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Ningfei JiDepartment of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Mao HuangDepartment of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Tiantian LiDepartment of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Xinyu WangDepartment of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jingli WenDepartment of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Wenjuan WuDivision of Intensive Care Unit, Wuhan Jin Yin-tan Hospital, Wuhan, China.
Mingjie WuThe Third Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, China.
Chaolin HuangThe Third Clinical Medical College, Nanjing University of Chinese Medicine, Nanjing, China.
Yu LiSchool of Medicine and Holistic Integrative Medicine, Nanjing University of Chinese Medicine, Nanjing, China.
Yun LiuDepartment of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Jinhai TangDepartment of Respiratory Medicine, The First Affiliated Hospital of Nanjing Medical University, Nanjing, China.
Nanjing Medical University · CNJiangsu Province Hospital · CNNanjing University of Chinese Medicine · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

This study aimed to detect, analyze, and correlate the clinical characteristics, blood coagulation functions, blood calcium levels, and inflammatory factors in patients with mild and severe COVID-19 infections. The enrolled COVID-19 infected patients were from Wuhan Jin Yin-tan Hospital (17 cases, Wuhan, China), Suzhou Infectious Disease Hospital (87 cases, Suzhou, China), and Xuzhou Infectious Disease Hospital (14 cases, Xuzhou, China). After admission, basic information was collected; X-ray and chest CT images were obtained; and data from routine blood tests, liver and kidney function, myocardial enzymes, electrolytes, blood coagulation function, (erythrocyte sedimentation rate) ESR, C-reactive protein (CRP), IL-6, procalcitonin (PCT), calcitonin, and other laboratory tests were obtained. The patients were grouped according to the clinical classification method based on the pneumonia diagnosis and treatment plan for new coronavirus infection (trial version 7) in China. The measurements from mild (56 cases) and severe cases (51 cases) were compared and analyzed. Most COVID-19 patients presented with fever. Chest X-ray and CT images showed multiple patchy and ground glass opacities in the lungs of COVID 19 infected patients, especially in patients with severe cases. Compared with patients with mild infection, patients with severe infection were older (

Indexed as

coagulation functionCOVID-19hypocalcemiainflammationmetabolic disorder

Identifiers

PMID34222271
PMCPMC8242574
OpenAlexW3170112469

What OpenQuestion holds

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LicenceCC BY
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.