Evidence map›Paper›PMID 34222248›Full record

ArticleFrontiers in cell and developmental biology2021

Generation of a Mouse Model to Study the Noonan Syndrome Gene

Mary Jo Talley, Diana Nardini, Nisha Shabbir, Lisa A Ehrman, Carlos E Prada, Ronald R Waclaw

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cell and developmental biology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.2field-weighted citation impact, top 52% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 2 citations in OpenAlex.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors at 2 institutions in 1 country.

Mary Jo TalleyGraduate Program in Molecular and Developmental Biology, Cincinnati Children's Hospital Research Foundation, University of Cincinnati College of Medicine, Cincinnati, OH, United States.
Diana NardiniDivision of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.
Nisha ShabbirDivision of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.
Lisa A EhrmanDivision of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.
Carlos E PradaDivision of Human Genetics, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.
Ronald R WaclawDivision of Experimental Hematology and Cancer Biology, Cincinnati Children's Hospital Medical Center, Cincinnati, OH, United States.
Cincinnati Children's Hospital Medical Center · USUniversity of Cincinnati Medical Center · US

Funding

Signaling pathways regulating oligodendrocyte development and functionR01NS088529 · NINDS · CINCINNATI CHILDRENS HOSP MED CTR · PI WACLAW, RONALD R · 2015 to 2019
$1.8M
NINDS NIH HHS R01 NS088529
6 · The paper itself

Abstract

The leucine zipper-like transcriptional regulator 1 (

Indexed as

astrocyteLZTR1MAPKNoonan syndromeoligodendrocyte

Identifiers

PMID34222248
PMCPMC8242193
OpenAlexW3167965372

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.