Evidence map›Paper›PMID 34222184›Full record

ArticleFrontiers in public health2021

Antimicrobial Resistance Profiles of Coagulase-Negative Staphylococci in Community-Based Healthy Individuals in Germany.

Gabriella Marincola, Olivia Liong, Christoph Schoen, Alaa Abouelfetouh, Aisha Hamdy, Freya D R Wencker, Tessa Marciniak, Karsten Becker, Robin Köck, Wilma Ziebuhr

Open access · goldAbstract read
In one paragraph

Article in Frontiers in public health, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 41 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
41citing papers in PubMed, 1 pooled it
3.6field-weighted citation impact, top 6% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

41 citing papers in PubMed, 1 synthesis or guideline pooled it, 59 citations in OpenAlex.

  1. Pooled it
  2. Multidrug Resistance andPathogens (Basel, Switzerland) · 2026
    Article
  3. Article
  4. Article
  5. Article
  6. First Report ofMicroorganisms · 2026
    Article
  7. Review
  8. Mechanisms of fusidic acid resistance.Biochemical Society transactions · 2025
    Review
  9. Article
  10. Characteristics ofInternational journal of molecular sciences · 2025
    Article
  11. Revealing the clinical relevance ofMicrobiology spectrum · 2025
    Article
  12. Article
  13. Genomic characterization of a multidrug-resistantFrontiers in microbiology · 2025
    Article
  14. Pathogenic potential of meat-borne coagulase negative staphylococci strains from slaughterhouse to fork.International microbiology : the official journal of the Spanish Society for Microbiology · 2024
    Article
  15. Review
  16. Article
  17. Article
  18. Article
  19. Article
  20. Manuka honey as a non-antibiotic alternative againstFrontiers in cellular and infection microbiology · 2024
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 5 institutions in 2 countries.

Gabriella MarincolaInstitute of Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Olivia LiongInstitute of Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Christoph SchoenInstitute of Hygiene and Microbiology, University of Würzburg, Würzburg, Germany.
Alaa AbouelfetouhDepartment of Microbiology and Immunology, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
Aisha HamdyDepartment of Microbiology and Immunology, Faculty of Pharmacy, Alexandria University, Alexandria, Egypt.
Freya D R WenckerInstitute of Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Tessa MarciniakInstitute of Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
Karsten BeckerFriedrich Loeffler-Institute of Medical Microbiology, University Medicine Greifswald, Greifswald, Germany.
Robin KöckDeutsches Rotes Kreuz (DRK) Kliniken Berlin, Berlin, Germany.
Wilma ZiebuhrInstitute of Molecular Infection Biology, University of Würzburg, Würzburg, Germany.
University of Würzburg · DEAlexandria University · EGFriedrich-Loeffler-Institut · DEGerman Red Cross · DEHelmholtz Centre for Infection Research · DE

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coagulase-negative staphylococci (CoNS) are common opportunistic pathogens, but also ubiquitous human and animal commensals. Infection-associated CoNS from healthcare environments are typically characterized by pronounced antimicrobial resistance (AMR) including both methicillin- and multidrug-resistant isolates. Less is known about AMR patterns of CoNS colonizing the general population. Here we report on AMR in commensal CoNS recovered from 117 non-hospitalized volunteers in a region of Germany with a high livestock density. Among the 69 individuals colonized with CoNS, 29 had reported contacts to either companion or farm animals. CoNS were selectively cultivated from nasal swabs, followed by species definition by 16S rDNA sequencing and routine antibiotic susceptibility testing. Isolates displaying phenotypic AMR were further tested by PCR for presence of selected AMR genes. A total of 127 CoNS were isolated and

Indexed as

Drug Resistance, BacterialStaphylococcal InfectionsAnimalsAnti-Bacterial AgentsCoagulaseGermanyHumansAnti-Bacterial AgentsCoagulaseantimicrobial resistancecoagulase-negative staphylococcicommunity settingsGermanyOne Health

Identifiers

PMID34222184
PMCPMC8247762
OpenAlexW3177443092

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.