Evidence map›Paper›PMID 34222132›Full record

ArticleClinical and experimental vaccine research2021

A possible protective role for Bacillus Calmette-Guérin therapy in urinary bladder cancer in the era of COVID-19: a brief report.

Solmaz Ohadian Moghadam, Behzad Abbasi, Ali Nowroozi, Erfan Amini, Mohammad Reza Nowroozi, Seyed Ali Momeni, Hassan Niroomand

Open access · diamondAbstract read
In one paragraph

Article in Clinical and experimental vaccine research, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
0.2field-weighted citation impact, top 50% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 3 citations in OpenAlex.

  1. Review
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 1 country.

Solmaz Ohadian MoghadamUro-Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0001-9745-7063
Behzad AbbasiUro-Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-7175-9984
Ali NowrooziUro-Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-7624-5026
Erfan AminiUro-Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0001-9647-0047
Mohammad Reza NowrooziUro-Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-6306-3426
Seyed Ali MomeniUro-Oncology Research Center, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-4995-4150
Hassan NiroomandTrauma Research Center, AJA University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0003-3429-6842
Tehran University of Medical Sciences · IRAja University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Given the systemic immunogenic effects of Bacillus Calmette-Guérin (BCG) therapy in patients with bladder cancer and its non-specific immunogenic effects in viral respiratory diseases, we aimed to study severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in bladder cancer patients with a history of BCG therapy. In the present study, all bladder cancer survivors with a history of BCG therapy were identified and included in the study according to the data recovered from the UORC (Uro-Oncology Research Center) registry database. These patients were followed up in terms of acquiring coronavirus disease 2019 (COVID-19). Among the studied patients, 102 eligible bladder cancer patients with a history of BCG therapy entered the study. The males constituted the majority of the patients (86.3%), and more than half of the study population (55.9%) were above 65 years old. Among the understudy patients, 12.7% were confirmed for COVID-19. The study results did not show a statistically significant association between the time and number of BCG therapy courses and SARS-CoV-2 infection. Although no statistically significant association was observed between receiving BCG therapy and developing COVID-19, the infection rate in patients who had recently received BCG therapy was lower than those who had received therapy more than a year ago.

Indexed as

BCG therapyCOVID-19Urinary bladder neoplasms

Identifiers

PMID34222132
PMCPMC8217577
OpenAlexW3177443753

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.