Evidence map›Paper›PMID 34222081›Full record

ArticleJournal of diabetes and metabolic disorders2021

Prospection of plasma proteins as biomarkers for diabetes mellitus monitoring.

Liliane de Paula Silva, Fabiane Gomes de Moraes Rego, Geraldo Picheth, Marcelo Müller-Santos, Dayane Alberton

Open access · greenAbstract read
In one paragraph

Article in Journal of diabetes and metabolic disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 6 papers.

0numbers the graph read from it
0cells of the map it votes in
6citing papers in PubMed
0.7field-weighted citation impact, top 29% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

6 citing papers in PubMed, 10 citations in OpenAlex.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Liliane de Paula SilvaGraduate Program in Pharmaceutical Science, Department of Clinical Analysis, Federal University of Paraná, Rua Prefeito Lothário Meissner, 632, Curitiba, PR 80210-170 Brazil.ORCID https://orcid.org/0000-0002-1531-4024
Fabiane Gomes de Moraes RegoGraduate Program in Pharmaceutical Science, Department of Clinical Analysis, Federal University of Paraná, Rua Prefeito Lothário Meissner, 632, Curitiba, PR 80210-170 Brazil.ORCID https://orcid.org/0000-0003-1726-8524
Geraldo PichethGraduate Program in Pharmaceutical Science, Department of Clinical Analysis, Federal University of Paraná, Rua Prefeito Lothário Meissner, 632, Curitiba, PR 80210-170 Brazil.ORCID https://orcid.org/0000-0003-1760-5906
Marcelo Müller-SantosGraduate Program in Sciences - Biochemistry, Department of Biochemistry and Molecular Biology, Federal University of Paraná, Curitiba, PR Brazil.ORCID https://orcid.org/0000-0001-9615-6007
Dayane AlbertonGraduate Program in Pharmaceutical Science, Department of Clinical Analysis, Federal University of Paraná, Rua Prefeito Lothário Meissner, 632, Curitiba, PR 80210-170 Brazil.ORCID 0000-0002-7250-8618
Universidade Federal do Paraná · BR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeThis prospective study aimed to detect and identify plasma proteins differentially expressed between groups of Brazilian diagnosed with type 1 (T1DM), type 2 (T2DM) diabetes with good and poor glycemic control and the non-diabetic group denominated control group (CG).

methodsPatients with T1DM and T2DM were subdivided according to their glycated haemoglobin (HbA

resultsAlpha 2 - Macroglobulin (AMG) was 1.3-fold more abundant in T1DM with HbA

conclusionIn summary, three positive acute-phase proteins, AMG, Cp and Hp were more abundant in diabetic individuals regardless of the diabetes type. The highest Hp abundance in both types of DM with HbA

Indexed as

Apolipoprotein A-ICeruloplasminGlycemic controlHaptoglobinsType 1 diabetesType 2 diabetes

Identifiers

PMID34222081
PMCPMC8212233
OpenAlexW3149535453

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.