Evidence map›Paper›PMID 34222066›Full record

ArticleJournal of diabetes and metabolic disorders2021

Assessment of fecal

Shahrbanoo Keshavarz Azizi Raftar, Zahra Hoseini Tavassol, Meysam Amiri, Hanieh-Sadat Ejtahed, Mehrangiz Zangeneh, Sedigheh Sadeghi, Fatemeh Ashrafian, Arian Kariman, Shohreh Khatami, Seyed Davar Siadat

Open access · greenAbstract read
In one paragraph

Article in Journal of diabetes and metabolic disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed, 29 citations in OpenAlex.

  1. Hesperetin mitigates IBD-associated bone loss viaJournal of orthopaedic translation · 2026
    Article
  2. Review
  3. PasteurizedFrontiers in immunology · 2026
    Article
  4. Article
  5. Article
  6. Frontiers in microbiology · 2025
    Review
  7. Investigating the role ofFrontiers in microbiology · 2025
    Article
  8. Review
  9. Review
  10. Article
  11. Article
  12. Article
  13. Article
  14. Review
  15. Article
  16. Health and Disease:Research (Washington, D.C.) · 2023
    Article
  17. Article
  18. Article
  19. Gut microbes
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 3 institutions in 1 country.

Shahrbanoo Keshavarz Azizi RaftarMicrobiology Research Center (MRC), Pasteur Institute of Iran, Tehran, Iran.ORCID https://orcid.org/0000-0002-4492-6716
Zahra Hoseini TavassolMicrobiology Research Center (MRC), Pasteur Institute of Iran, Tehran, Iran.ORCID https://orcid.org/0000-0002-2432-2114
Meysam AmiriMicrobiology Research Center (MRC), Pasteur Institute of Iran, Tehran, Iran.ORCID https://orcid.org/0000-0002-7417-9643
Hanieh-Sadat EjtahedObesity and Eating Habits Research Center, Endocrinology and Metabolism Clinical Sciences Institute, Tehran University of Medical Sciences, Tehran, Iran.ORCID https://orcid.org/0000-0002-6395-4915
Mehrangiz ZangenehDepartment of Infectious Disease, Faculty of Medicine, Tehran Medical science, Islamic Azad University, Tehran, Iran.ORCID https://orcid.org/0000-0001-7673-4287
Sedigheh SadeghiDepartment of Biochemistry, Pasteur Institute of Iran, Tehran, Iran.ORCID https://orcid.org/0000-0002-6179-4372
Fatemeh AshrafianMicrobiology Research Center (MRC), Pasteur Institute of Iran, Tehran, Iran.ORCID https://orcid.org/0000-0003-0310-0181
Arian KarimanTehran university of Medical science, Tehran, Iran.
Shohreh KhatamiDepartment of Biochemistry, Pasteur Institute of Iran, Tehran, Iran.ORCID https://orcid.org/0000-0001-9514-7571
Seyed Davar SiadatMicrobiology Research Center (MRC), Pasteur Institute of Iran, Tehran, Iran.ORCID https://orcid.org/0000-0002-6892-5603
Pasteur Institute of Iran · IRIslamic Azad University Medical Branch of Tehran · IRTehran University of Medical Sciences · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

objectivesOsteoporosis is characterized by slow deterioration in bone mass and disruption of its structure, leading to an increased risk of bone fractures. Gut microbiota plays an important role in the transport and absorption of nutrients needed for bone health.

methodsA total of 36 subjects including eight with osteoporosis (three men and five women), eight with osteopenia (two men and six women), and 20 normal controls (six men and 14 women) were selected. Microbial genome was extracted from fresh stool samples. The bacterial load was determined by quantitative real-time PCR using 16S rRNA specific primers.

resultsThe participants' mean age in the osteoporosis, osteopenia and control groups were 61.71, 45 and 45.05 years, respectively. The majority of osteoporosis patients were post-menopause women, while in osteopenia group was pre-menopause. There were significant differences in terms of age, T-score, Z-score, and menopause among groups (

conclusionsIn conclusion, however, there was no statistically significant difference between the study groups; it seems that the load of

Indexed as

Akkermansia muciniphilaBone healthIntestinal microbiota

Identifiers

PMID34222066
PMCPMC8212221
OpenAlexW3121669174

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.