Evidence map›Paper›PMID 34222061›Full record

ArticleJournal of diabetes and metabolic disorders2021

Association of ADIPOQ rs266729 and rs1501299 gene polymorphisms and circulating adiponectin level with the risk of type 2 diabetes in a population of Iran: a case-control study.

Mahrokh Alimi, Mohammad Taghi Goodarzi, Mehdi Nekoei

Open access · greenAbstract read
In one paragraph

Article in Journal of diabetes and metabolic disorders, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 17 papers, 2 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
17citing papers in PubMed, 2 pooled it
2.4field-weighted citation impact, top 11% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

17 citing papers in PubMed, 2 syntheses or guidelines pooled it, 26 citations in OpenAlex.

  1. Pooled it
  2. A Systematic Narrative Review onEndocrine, metabolic & immune disorders drug targets · 2024
    Pooled it
  3. CTNNB1 Genetic Variation and Its Interaction With DLK1 in Type 2 Diabetes Mellitus.FASEB journal : official publication of the Federation of American Societies for Experimental Biology · 2026
    Article
  4. Article
  5. An Exploratory Study ofInternational journal of molecular sciences · 2026
    Article
  6. Article
  7. Article
  8. Article
  9. Association ofIranian journal of public health · 2024
    Review
  10. Article
  11. Association ofGenes · 2024
    Article
  12. Review
  13. Review
  14. Review
  15. Effect of Genetic Variations in theDiabetes, metabolic syndrome and obesity : targets and therapy · 2022
    Article
  16. Article
  17. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mahrokh AlimiDepartment of Chemistry, Shahrood Branch, Islamic Azad University, Shahrood, IR Iran.
Mohammad Taghi GoodarziDepartment of Biochemistry, Shahrood Branch, Islamic Azad University, Shahrood, IR Iran.
Mehdi NekoeiDepartment of Chemistry, Shahrood Branch, Islamic Azad University, Shahrood, IR Iran.
Islamic Azad University, Shahrood · IR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeMutation in various regions of the adiponectin (ADIPOQ) gene is described to be associated with type 2 diabetes (T2D). Our aim was to investigate the association between rs1501299 (SNP + 276 G > T) and rs266729 (SNP-11377 C > G) polymorphisms of ADIPOQ gene and susceptibility to T2D in an Iranian population.

methodsThis is a case-control study. A total of 210 subjects including 100 patients with T2D and 110 healthy controls were selected from an Iranian population. SNP-11377 C > G and SNP + 276 G > T polymorphisms were investigated using the Tetra ARMS-PCR method.

resultsThe genotypes frequency of the SNP-11377 C > G polymorphism (

conclusionWe concluded that ADIPOQ rs266729 (SNP-11377 C > G) gene polymorphism but no rs1501299 is associated with increased risk of T2D in our population.

Indexed as

AdiponectinPolymorphismrs1501299rs266729Type 2 diabetes

Identifiers

PMID34222061
PMCPMC8212218
OpenAlexW3127392130

What OpenQuestion holds

Textmetadata
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.