Evidence map›Paper›PMID 34222050›Full record

ArticleFrontiers in cellular and infection microbiology2021

Characterisation of Bacteriophage-Encoded Depolymerases Selective for Key

George Blundell-Hunter, Mark C Enright, David Negus, Matthew J Dorman, Gemma E Beecham, Derek J Pickard, Phitchayapak Wintachai, Supayang P Voravuthikunchai, Nicholas R Thomson, Peter W Taylor

Open access · goldAbstract read
In one paragraph

Article in Frontiers in cellular and infection microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 22 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
22citing papers in PubMed, 1 pooled it
3.4field-weighted citation impact, top 8% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

22 citing papers in PubMed, 1 synthesis or guideline pooled it, 30 citations in OpenAlex.

  1. Pooled it
  2. Article
  3. Review
  4. Article
  5. Article
  6. Article
  7. Fast and accurateMicrobial genomics · 2025
    Article
  8. Mobile genetic elements inJournal of bacteriology · 2025
    Review
  9. Review
  10. Article
  11. Phage-encoded depolymerases as a strategy for combating multidrug-resistantFrontiers in cellular and infection microbiology · 2024
    Review
  12. Article
  13. Article
  14. Article
  15. Insights into theInternational journal of molecular sciences · 2023
    Article
  16. Article
  17. Article
  18. Article
  19. Article
  20. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors at 6 institutions in 2 countries.

George Blundell-HunterSchool of Pharmacy, University College London, London, United Kingdom.
Mark C EnrightDepartment of Life Sciences, Manchester Metropolitan University, Manchester, United Kingdom.
David NegusSchool of Science & Technology, Nottingham Trent University, Nottingham, United Kingdom.
Matthew J DormanParasites and Microbes Programme, Wellcome Sanger Institute, Hinxton, United Kingdom.
Gemma E BeechamSchool of Pharmacy, University College London, London, United Kingdom.
Derek J PickardDepartment of Medicine, University of Cambridge, Addenbrooke's Hospital, Cambridge, United Kingdom.
Phitchayapak WintachaiFaculty of Science, Prince of Songkla University, Songkhla, Thailand.
Supayang P VoravuthikunchaiFaculty of Science, Prince of Songkla University, Songkhla, Thailand.
Nicholas R ThomsonParasites and Microbes Programme, Wellcome Sanger Institute, Hinxton, United Kingdom.
Peter W TaylorSchool of Pharmacy, University College London, London, United Kingdom.
University College London · GBPrince of Songkla University · THWellcome Sanger Institute · GBAddenbrooke's Hospital · GBManchester Metropolitan University · GBNottingham Trent University · GB

Funding

Medical Research Council MR/N012542/1Medical Research Council MR/R009937/1Wellcome TrustWellcome Trust 206194
6 · The paper itself

Abstract

Capsular polysaccharides enable clinically important clones of

Indexed as

BacteriophagesKlebsiella InfectionsBacterial CapsulesGenome, ViralHost SpecificityHumansKlebsiella pneumoniaeThailandalternative antibacterial therapybacteriophagecapsular polysaccharidecapsule depolymerasejumbo phageKlebsiella pneumoniaewhole-genome sequencing (WGS)

Identifiers

PMID34222050
PMCPMC8253255
OpenAlexW3177111506

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.