Evidence map›Paper›PMID 34221969›Full record

ArticleFrontiers in oncology2021

The ETS Inhibitor YK-4-279 Suppresses Thyroid Cancer Progression Independent of

Junyu Xue, Shiyong Li, Peijie Shi, Mengke Chen, Shuang Yu, Shubin Hong, Yanbing Li, Rengyun Liu, Haipeng Xiao

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.6field-weighted citation impact, top 16% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 12 citations in OpenAlex.

  1. BRAF-induced EHF Expression Affects TERT in Aggressive Papillary Thyroid Cancer.The Journal of clinical endocrinology and metabolism · 2025
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Junyu XueDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Shiyong LiInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Peijie ShiDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Mengke ChenInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Shuang YuDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Shubin HongDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Yanbing LiDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Rengyun LiuInstitute of Precision Medicine, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Haipeng XiaoDepartment of Endocrinology, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou, China.
Sun Yat-sen University · CNThe First Affiliated Hospital, Sun Yat-sen University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hotspot mutations in the core promoter region of the

Indexed as

apoptosisE-twenty-six transcription factortelomerase reverse transcriptasethyroid cancerYK-4-279

Identifiers

PMID34221969
PMCPMC8242932
OpenAlexW3170543489

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.