Evidence map›Paper›PMID 34221964›Full record

ArticleFrontiers in oncology2021

Carcinoembryonic Antigen Related Cell Adhesion Molecule 6 Promotes Carcinogenesis of Gastric Cancer and Anti-CEACAM6 Fluorescent Probe Can Diagnose the Precancerous Lesions.

Fangmei An, Chuwei Zheng, Guoqiang Zhang, Liangyun Zhou, Yuqing Wu, Zheng Hou, Zhiyi Zhou, Ke Chen, Qiang Zhan

Open access · goldAbstract read
In one paragraph

Article in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 11 papers.

0numbers the graph read from it
0cells of the map it votes in
11citing papers in PubMed
1.5field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

11 citing papers in PubMed, 23 citations in OpenAlex.

  1. Review
  2. Article
  3. Article
  4. Article
  5. Article
  6. Review
  7. The emerging roles of CEACAM6 in human cancer (Review).International journal of oncology · 2024
    Review
  8. Article
  9. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 3 institutions in 1 country.

Fangmei AnDepartment of Gastroenterology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Chuwei ZhengDepartment of Gastroenterology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Guoqiang ZhangDepartment of Gastroenterology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Liangyun ZhouDepartment of Gastroenterology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Yuqing WuSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, China.
Zheng HouSuzhou Institute of Biomedical Engineering and Technology, Chinese Academy of Sciences, Suzhou, China.
Zhiyi ZhouDepartment of Pathology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Ke ChenDepartment of Gastroenterology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Qiang ZhanDepartment of Gastroenterology, Wuxi People's Hospital Affiliated to Nanjing Medical University, Wuxi, China.
Wuxi People's Hospital · CNNanjing Medical University · CNChinese Academy of Sciences · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The diagnosis of precancerous lesions or early gastric cancer (EGC) is very important for patient survival. Molecular imaging is a visualized method that can easily and precisely diagnose tumors. However, there are currently few studies about molecular imaging diagnosis of EGC. Here, we studied the expression of carcinoembryonic antigen related cell adhesion molecule 6 (CEACAM6) in the progression of GC. Then, the regulatory roles of CEACAM6 in GC cells were investigated. Furthermore, both the fluorescent-labeled and near infrared molecular-labeled probes were synthesized, and the diagnostic value of anti-CEACAM6 probes in GC was evaluated

Indexed as

CEACAM6fluorescent-labeled probegastric cancernear infrared-labeled probeprecancerous lesions

Identifiers

PMID34221964
PMCPMC8248535
OpenAlexW3175698190

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.