Evidence map›Paper›PMID 34221959›Full record

ReviewFrontiers in oncology2021

Barrett's Esophagus and Intestinal Metaplasia.

Lu Zhang, Binyu Sun, Xi Zhou, QiongQiong Wei, Sicheng Liang, Gang Luo, Tao Li, Muhan Lü

Abstract readReview
In one paragraph

Review in Frontiers in oncology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 13 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

13 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
  2. Review
  3. Beyond PPIs: New Options for Treating GERD.Federal practitioner : for the health care professionals of the VA, DoD, and PHS · 2025
    Article
  4. Article
  5. Review
  6. Irregular Z-Line: To Biopsy or Not to Biopsy?Digestive diseases and sciences · 2024
    Review
  7. Article
  8. [Barrett's esophagus: histochemical difference between goblet cells and blue cells].Revista medica del Instituto Mexicano del Seguro Social · 2023
    Observational
  9. Article
  10. Review
  11. Review
  12. Review
  13. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Lu ZhangDepartment of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Luzhou City, China.
Binyu SunDepartment of Endoscope, Public Health Clinical Medical Center of Chengdu, Chengdu City, China.
Xi ZhouDepartment of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Luzhou City, China.
QiongQiong WeiDepartment of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Luzhou City, China.
Sicheng LiangDepartment of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Luzhou City, China.
Gang LuoDepartment of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Luzhou City, China.
Tao LiDepartment of Anesthesiology, West China Hospital, Sichuan University, Chengdu City, China.
Muhan LüDepartment of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Luzhou City, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Intestinal metaplasia refers to the replacement of the differentiated and mature normal mucosal epithelium outside the intestinal tract by the intestinal epithelium. This paper briefly describes the etiology and clinical significance of intestinal metaplasia in Barrett's esophagus. This article summarizes the impact of intestinal metaplasia on the diagnosis, monitoring, and treatment of Barrett's esophagus according to different guidelines. We also briefly explore the basis for the endoscopic diagnosis of intestinal metaplasia in Barrett's esophagus. The identification techniques of goblet cells in Barrett's esophagus are also elucidated by some scholars. Additionally, we further elaborate on the current treatment methods related to Barrett's esophagus.

Indexed as

Barrett’s esophagus (BE)endoscopy and pathological identificationintestinal metaplasia (IM)monitoringtreatment

Identifiers

PMID34221959
PMCPMC8252963

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.