ReviewAnesthesiology and pain medicine2021
Surgical and Non-surgical Treatment Options for Piriformis Syndrome: A Literature Review.
Review in Anesthesiology and pain medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers, 1 of them a synthesis that pooled it.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
20 citing papers in PubMed, 1 synthesis or guideline pooled it, 52 citations in OpenAlex.
- Piriformis syndrome: a systematic review of case reports.BMC surgery · 2025Pooled it
- Prevalence and Clinical Patterns of Piriformis Syndrome Among Actively Competing and Retired Elite Hockey Players.Sports (Basel, Switzerland) · 2026Article
- Frequency of posterior interosseous nerve syndrome and its impact on clinical outcomes in patients with lateral epicondylitis: A prospective, controlled, electrophysiological study.Acta neurologica Belgica · 2026Article
- Endoscopic vs Open Surgeries for Piriformis Syndrome: A Systematic Review and Meta-Analysis.Advances in orthopedics · 2026Review
- Article
- Differential Diagnosis of Posterior Buttock Pain: A Conceptual Review Based on Topographic Localization of Pain, Is It Really the Sacroiliac Joint?International journal of spine surgery · 2025Article
- Piriformis Syndrome Is Often Overlooked as a Cause of Gluteal Pain and Sciatica: Diagnostic Challenges and the Role of Imaging-A Narrative Review.HSS journal : the musculoskeletal journal of Hospital for Special Surgery · 2025Review
- Comparison of Pulsed Radiofrequency and Endoscopic Piriformis Release for Refractory Piriformis Syndrome: A Propensity Score-Matched Retrospective Cohort Study.Journal of clinical medicine · 2025Article
- Piriformis preservation in total hip arthroplasty: do we have a new concept? An update on anatomy, function and clinical outcomes.EFORT open reviews · 2025Article
- Ultrasound-guided nerve hydrodissection for sciatic neuropathy caused by piriformis rhabdomyolysis: A case report.Joint diseases and related surgery · 2025Article
- Endoscopic Technique: Sciatic Neurolysis and Piriformis Tendon Release for Treating Piriformis Syndrome.Arthroscopy techniques · 2024Article
- Testing the Safety of Piriformis Dry Needling Interventions: An Observational Study Evaluating the Predictive Value of Anthropometric and Demographic Factors.Journal of clinical medicine · 2024Article
- Effects of Radial Extracorporeal Shockwave Therapy on Piriformis Syndrome: A Single-Case Experimental Design.Cureus · 2024Article
- Sciatic Nerve and Its Anatomical Variations: In-Depth Understanding Acquired During Dissection Classes.Cureus · 2024Article
- Ultrasound-Guided Sciatic Nerve Hydrodissection Can Improve the Clinical Outcomes of Patients with Deep Gluteal Syndrome: A Case-Series Study.Diagnostics (Basel, Switzerland) · 2024Article
- Deep Gluteal syndrome: An underestimated cause of posterior hip pain.Turkish journal of physical medicine and rehabilitation · 2024Review
- Evaluation of the Efficacy of Ultrasound-Guided Dry Needling Therapy and Exercise in Piriformis Muscle Syndrome.Cureus · 2023Article
- Trigger Point Injections.Physical medicine and rehabilitation clinics of North America · 2022Review
- Effectiveness of Hydro-Dissection of the Piriformis Muscle Plus Low-Dose Local Anesthetic Injection for Piriformis Syndrome: A Report of 2 Cases.The American journal of case reports · 2022Article
- Overview of the anatomical basis of the piriformis syndrome-dissection with magnetic resonance correlation.Experimental and therapeutic medicine · 2022Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
11 authors at 5 institutions in 3 countries.
Funding
No grant is acknowledged in the PubMed record.
Abstract
contextPiriformis syndrome is a solely clinical diagnosis that often eludes the practitioner and goes underdiagnosed. PS is a pain syndrome and for those it affects, causes persistent pain and limits daily activity and work capacity. It is a form of deep gluteal syndrome that needs to be considered on the differential of low back pain as it comprises between 0.3% - 6% of all low back pain cases and is frequently underdiagnosed. Piriformis syndrome may be primary due anatomic anomalies or secondary, though the majority of cases are secondary to some insult. The objective of this manuscript is to provide a description of the epidemiology and presentation of piriformis as well as both non-operative and operative treatment options. We review all of the recent clinical evidence regarding the aforementioned therapies. EVIDENCE ACQUISITION: Literature searches were performed using the below MeSH Terms using Mendeley version 1.19.4. Search fields were varied until further searches revealed no new articles. All articles were screened by title and abstract. Decision was made to include an article based on its relevance and the list of final articles was approved three of the authors. This included reading the entirety of the article. Any question regarding the inclusion of an article was discussed by all authors until an agreement was reached.
resultsMedical management and physical therapy show some promise; however, when conservative treatment fails minimally invasive methods such as steroid injections, botulinum toxin injections, dry needling are all efficacious and there is substantial clinical evidence regarding these therapies. In those patients in which minimally invasive techniques do not result in an adequate relief of pain and return of function, endoscopic release can be considered. Endoscopic release is far superior to open release of the piriformis syndrome given the higher success and lower rate of complications.
conclusionsPiriformis syndrome is an important differential diagnosis in the work up of lower back pain and should not be ruled out with proper examination and testing. Clinicians should consider medical management and conservative management in the initial treatment plan for piriformis syndrome. There are many options within the conservative management and the literature shows much promise regarding these. Physical therapy, steroid injections, botulinum toxin injections, and dry needling are all potentially effective therapies with few adverse effects. Surgical options remain as gold standard, but only when conservative management has failed and the symptoms are significant to affect daily living activities. Endoscopic decompression of the sciatic nerve with or without release of the piriformis muscle has a reported high likelihood of success and a low complication rate. Current literature supports the preference of the endoscopic approach over the open approach due to improved outcomes and decreased complications. Further research is to well define the metrics for the diagnosis of piriformis syndrome and may include a need to develop diagnostic criteria.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.