Evidence map›Paper›PMID 34221740›Full record

ArticlePeerJ2021

Genomic evidence of adaptive evolution in the reptilian SOCS gene family.

Tian Xia, Lei Zhang, Guolei Sun, Xiufeng Yang, Honghai Zhang

Open access · goldAbstract read
In one paragraph

Article in PeerJ, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
0.2field-weighted citation impact, top 47% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 3 citations in OpenAlex.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 1 institution in 1 country.

Tian XiaCollege of Life Science, Qufu Normal University, Qufu, Shandong, China.ORCID 0000-0002-0097-6949
Lei ZhangCollege of Life Science, Qufu Normal University, Qufu, Shandong, China.
Guolei SunCollege of Life Science, Qufu Normal University, Qufu, Shandong, China.
Xiufeng YangCollege of Life Science, Qufu Normal University, Qufu, Shandong, China.ORCID 0000-0001-7521-954X
Honghai ZhangCollege of Life Science, Qufu Normal University, Qufu, Shandong, China.
Qufu Normal University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The suppressor of the cytokine signaling (SOCS) family of proteins play an essential role in inhibiting cytokine receptor signaling by regulating immune signal pathways. Although SOCS gene functions have been examined extensively, no comprehensive study has been performed on this gene family's molecular evolution in reptiles. In this study, we identified eight canonical SOCS genes using recently-published reptilian genomes. We used phylogenetic analysis to determine that the SOCS genes had highly conserved evolutionary dynamics that we classified into two types. We identified positive

Indexed as

Adaptive evolutionPAMLReptilesSOCS gene family

Identifiers

PMID34221740
PMCPMC8236234
OpenAlexW3177450564

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.