Evidence map›Paper›PMID 34221696›Full record

ArticleTremor and other hyperkinetic movements (New York, N.Y.)2021

Does Raising the Arms Modify Head Tremor Severity in Cervical Dystonia?

Elizabeth Cisneros, Jeanne P Vu, Ha Yeon Lee, Qiyu Chen, Casey N Benadof, Zheng Zhang, Emily A Pettitt, Subhagya K Joshi, Richard L Barbano, Joseph Jankovic and 8 more

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Tremor and other hyperkinetic movements (New York, N.Y.), 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
0.3field-weighted citation impact, top 39% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed, 3 citations in OpenAlex.

  1. Isolated Cervical Dystonia: Diagnosis and Classification.Movement disorders : official journal of the Movement Disorder Society · 2023
    Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors at 8 institutions in 1 country.

Elizabeth CisnerosInstitute for Neural Computation, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0001-9466-9116
Jeanne P VuInstitute for Neural Computation, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0003-2665-2763
Ha Yeon LeeInstitute for Neural Computation, University of California, San Diego, La Jolla, CA, USA.
Qiyu ChenInstitute for Neural Computation, University of California, San Diego, La Jolla, CA, USA.
Casey N BenadofInstitute for Neural Computation, University of California, San Diego, La Jolla, CA, USA.
Zheng ZhangInstitute for Neural Computation, University of California, San Diego, La Jolla, CA, USA.
Emily A PettittInstitute for Neural Computation, University of California, San Diego, La Jolla, CA, USA.
Subhagya K JoshiInstitute for Neural Computation, University of California, San Diego, La Jolla, CA, USA.
Richard L BarbanoDepartment of Neurology, University of Rochester, Rochester, NY, USA.
Joseph JankovicParkinson's Disease Center and Movement Disorders Clinic, Department of Neurology, Baylor College of Medicine, Houston, TX, USA.
Hyder A JinnahDepartments of Neurology and Human Genetics, Emory University, Atlanta, GA, USA.ORCID 0000-0003-1531-3969
Joel S PerlmutterDepartment of Neurology, Washington University School of Medicine, St. Louis, MO, USA.
Brian D BermanDepartment of Neurology, Virginia Commonwealth University, Richmond, VA, USA.ORCID 0000-0002-0602-9942
Abhimanyu MahajanDepartment of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.ORCID 0000-0001-8807-6672
Christopher G GoetzDepartment of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.ORCID 0000-0003-4457-5511
Glenn T StebbinsDepartment of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
Cynthia L ComellaDepartment of Neurological Sciences, Rush University Medical Center, Chicago, IL, USA.
David A PetersonInstitute for Neural Computation, University of California, San Diego, La Jolla, CA, USA.ORCID 0000-0001-8151-4078
University of California San Diego · USRush University Medical Center · USBaylor College of Medicine · USEmory University · USSalk Institute for Biological Studies · USUniversity of Rochester · USVirginia Commonwealth University · USWashington University in St. Louis · US

Funding

Dystonia Coalition- Pilot ProjectU54NS116025 · NINDS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2019 to 2023
$7.1M
Dystonia CoalitionU54NS065701 · NINDS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2009 to 2014
$7.0M
Dystonia CoalitionU54TR001456 · NCATS · EMORY UNIVERSITY · PI JINNAH, HYDER A · 2015 to 2016
$2.5M
NCATS NIH HHS U54 TR001456NINDS NIH HHS U54 NS065701NINDS NIH HHS U54 NS116025
6 · The paper itself

Abstract

Background: A defining characteristic of dystonia is its position-dependence. In cervical dystonia (CD), sensory tricks ameliorate head tremor (HT). But it remains unknown whether raising the arms alone has the same impact. Methods: We analyzed data collected from patients enrolled by the Dystonia Coalition. For 120 patients with HT, we assessed how raising their arms without touching their head changed their HT severity. Results: Forty-eight out of 120 patients exhibited changes in HT severity when raising their arms. These patients were more likely to exhibit decreases in HT severity (N = 35) than increases (N = 13, χ Discussion: Raising the arms without touching the head is a posture that can reduce HT severity in some CD patients. Our results extend the concept of position-dependent motor symptoms in CD to include the position of the arms. Highlights: Head tremor (HT) is a prevalent symptom of cervical dystonia (CD) that can often be disabling. This study demonstrates that raising the arms without touching the head is a posture that can reduce HT severity in some CD patients. Our findings also identify a novel form of position-dependence in CD.

Indexed as

Dystonic DisordersTorticollisHumansPostureTouchTremorcervical dystoniadystonic tremorhead tremorposture

Identifiers

PMID34221696
PMCPMC8231450
OpenAlexW3174034607

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.