Evidence map›Paper›PMID 34221667›Full record

ArticleBiomedical optics express2021

The LUCA device: a multi-modal platform combining diffuse optics and ultrasound imaging for thyroid cancer screening.

Lorenzo Cortese, Giuseppe Lo Presti, Marta Zanoletti, Gloria Aranda, Mauro Buttafava, Davide Contini, Alberto Dalla Mora, Hamid Dehghani, Laura Di Sieno, Sixte de Fraguier and 10 more

Registry-linked trialAbstract read
In one paragraph

Article in Biomedical optics express, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06360809 (Prehabilitation Exercise Program in Breast Cancer), which is not on this map. Cited by 13 papers.

0numbers the graph read from it
0cells of the map it votes in
13citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06360809 naunknown statusnot on this mapstarted 2024, after this paper: background citation

Prehabilitation Exercise Program in Breast Cancer: Effects on Quality of Life and Tumor Microenvironment (PEP_BC)

TypeinterventionalSponsorInstitut Nacional d'Educacio Fisica de CatalunyaRan2024 to 2025Enrolled76ConditionsBreast CancerArmsPrehabilitation exercise program
3 · Its place in the literature

Who cites it

13 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

20 authors.

Lorenzo CorteseICFO-Institut de Ciències Fotòniques, The Barcelona Institute of Science and Technology, 08860 Castelldefels (Barcelona), Spain.ORCID https://orcid.org/0000-0001-9258-0863
Giuseppe Lo PrestiICFO-Institut de Ciències Fotòniques, The Barcelona Institute of Science and Technology, 08860 Castelldefels (Barcelona), Spain.
Marta ZanolettiPolitecnico di Milano, Dipartimento di Fisica, 20133 Milano, Italy.
Gloria ArandaIDIBAPS, Fundació Clínic per la Recerca Biomèdica, Barcelona, Spain.
Mauro ButtafavaPolitecnico di Milano, Dipartimento di Elettronica Informazione e Bioingegneria, 20133 Milano, Italy.ORCID https://orcid.org/0000-0002-5446-8026
Davide ContiniPolitecnico di Milano, Dipartimento di Fisica, 20133 Milano, Italy.ORCID https://orcid.org/0000-0003-1209-9397
Alberto Dalla MoraPolitecnico di Milano, Dipartimento di Fisica, 20133 Milano, Italy.ORCID https://orcid.org/0000-0002-2783-6217
Hamid DehghaniUniversity of Birmingham, School of Computer Science, Edgbaston, Birmingham, B15 2TT, UK.ORCID https://orcid.org/0000-0003-4117-0412
Laura Di SienoPolitecnico di Milano, Dipartimento di Fisica, 20133 Milano, Italy.ORCID https://orcid.org/0000-0002-3028-3705
Sixte de FraguierIMV Imaging, 16000 Angoulême, France.
Felicia A HanzuIDIBAPS, Fundació Clínic per la Recerca Biomèdica, Barcelona, Spain.
Mireia Mora PortaIDIBAPS, Fundació Clínic per la Recerca Biomèdica, Barcelona, Spain.
An Nguyen-DinhVERMON S.A., 37000 Tours, France.
Marco RennaPolitecnico di Milano, Dipartimento di Elettronica Informazione e Bioingegneria, 20133 Milano, Italy.
Bogdan RosinskiVERMON S.A., 37000 Tours, France.
Mattia SquarciaIDIBAPS, Fundació Clínic per la Recerca Biomèdica, Barcelona, Spain.
Alberto TosiPolitecnico di Milano, Dipartimento di Elettronica Informazione e Bioingegneria, 20133 Milano, Italy.
Udo M WeigelHemoPhotonics S.L., 08860 Castelldefels (Barcelona), Spain.
Stanislaw WojtkiewiczUniversity of Birmingham, School of Computer Science, Edgbaston, Birmingham, B15 2TT, UK.ORCID https://orcid.org/0000-0002-5556-4730
Turgut DurduranICFO-Institut de Ciències Fotòniques, The Barcelona Institute of Science and Technology, 08860 Castelldefels (Barcelona), Spain.ORCID https://orcid.org/0000-0001-5838-1027

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

We present the LUCA device, a multi-modal platform combining eight-wavelength near infrared time resolved spectroscopy, sixteen-channel diffuse correlation spectroscopy and a clinical ultrasound in a single device. By simultaneously measuring the tissue hemodynamics and performing ultrasound imaging, this platform aims to tackle the low specificity and sensitivity of the current thyroid cancer diagnosis techniques, improving the screening of thyroid nodules. Here, we show a detailed description of the device, components and modules. Furthermore, we show the device tests performed through well established protocols for phantom validation, and the performance assessment for

Identifiers

PMID34221667
PMCPMC8221941

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.