Evidence map›Paper›PMID 34221630›Full record

ArticleSurgical neurology international2021

Intravenous versus inhalational anesthesia trial for outcome following intracranial aneurysm surgery: A prospective randomized controlled study.

Hemant Bhagat, Tanavi Sharma, Shalvi Mahajan, Munish Kumar, Poonam Saharan, Avanish Bhardwaj, Naresh Sachdeva, Komal Gandhi, Kiran Jangra, Nidhi Bidyut Panda and 3 more

Open access · hybridAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical neurology international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed, 1 pooled it
2.3field-weighted citation impact, top 10% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed, 1 synthesis or guideline pooled it, 25 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Review
  5. Observational
  6. Article
  7. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

13 authors at 1 institution in 1 country.

Hemant BhagatDepartment of Anesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh.
Tanavi SharmaDepartment of Anesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh.
Shalvi MahajanDepartment of Anesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh.
Munish KumarDepartment of Anesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh.
Poonam SaharanDepartment of Anesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh.
Avanish BhardwajDepartment of Anesthesia and Critical Care, Command Hospital (Airforce), Bengaluru, Karnataka, India.
Naresh SachdevaDepartment of Endocrinology, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Komal GandhiDepartment of Anesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh.
Kiran JangraDepartment of Anesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh.
Nidhi Bidyut PandaDepartment of Anesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh.
Navneet SinglaDepartment of Neurosurgery Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Kamal KishoreDepartment of Biostatistics, Postgraduate Institute of Medical Education and Research, Chandigarh, India.
Nidhi SinghDepartment of Anesthesia and Intensive Care, Postgraduate Institute of Medical Education and Research, Chandigarh.
Post Graduate Institute of Medical Education and Research · IN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundFor maintenance of anesthesia for intracranial aneurysmal neck clipping, both intravenous and inhalational anesthetics are in vogue. We aimed to evaluate the superiority of one agent over the other for long-term neurological outcomes in these patients.

methodsThis prospective assessor-blind randomized study was conducted in 106 patients of 18-65 years of age with World Federation of Neurosurgeons Grade I-II of subarachnoid hemorrhage. After written informed consent, the patients were randomized into - intravenous group (Propofol) and inhalational group (Desflurane). The primary outcome was to study neurological outcome using Glasgow outcome scale (GOS) at 3 months following discharge while secondary outcomes included intraoperative brain condition, intraoperative hemodynamics, duration of hospital stay, Modified Rankin Score (MRS) at discharge, MRS, and Barthel's index at 3 months following discharge and estimation of perioperative biomarkers of brain injury.

resultsThe GOS at 3 months was 5 (5.00-5.00) in the propofol group and 5 (4.00-5.00) in the desflurane group (

conclusionThe long-term neurological outcome of good grade aneurysm patients undergoing craniotomy and clipping remains comparable with the use of either propofol or desflurane. The effect of the two anesthetic agents on the various clinical parameters and the biomarkers of brain injury is also similar.

Indexed as

Aneurysmal subarachnoid hemorrhageDesfluraneNeurological outcomeNeuronal injuryPropofol

Identifiers

PMID34221630
PMCPMC8247687
OpenAlexW3175247765

What OpenQuestion holds

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LicenceCC BY-NC-SA
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.