Evidence map›Paper›PMID 34221587›Full record

ArticleSurgical neurology international2021

Spontaneous thoracolumbar epidural hematoma in an apixaban anticoagulated patient.

Andreas Theofanopoulos, Petros Zampakis, Eleftheria Antoniadou, Dimitrios Papadakos, Dionysia Fermeli, Constantine Constantoyannis, Lambros Messinis, Vasileios Panagiotopoulos

Open access · hybridAbstract readCase Reports
PubMed Full text at PMC Publisher
In one paragraph

Article in Surgical neurology international, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed, 1 pooled it
0.4field-weighted citation impact, top 38% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed, 1 synthesis or guideline pooled it, 3 citations in OpenAlex.

  1. Pooled it
  2. Review
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors at 1 institution in 1 country.

Andreas TheofanopoulosDepartment of Neurosurgery, University of Patras, University Hospital of Patras, Achaia, Greece.
Petros ZampakisDepartment of Radiology and Interventional Neuroradiology, University of Patras, University Hospital of Patras, Achaia, Greece.
Eleftheria AntoniadouDepartment of Rehabilitation, Rehabilitation Clinic, University of Patras, University Hospital of Patras, Achaia, Greece.
Dimitrios PapadakosDepartment of Neurosurgery, University of Patras, University Hospital of Patras, Achaia, Greece.
Dionysia FermeliDepartment of Neurosurgery, University of Patras, University Hospital of Patras, Achaia, Greece.
Constantine ConstantoyannisDepartment of Neurosurgery, University of Patras, University Hospital of Patras, Achaia, Greece.
Lambros MessinisDepartment of Neurology and Psychiatry, Neuropsychology Section, University of Patras, University Hospital of Patras, Patras, Achaia, Greece.
Vasileios PanagiotopoulosDepartment of Neurosurgery and Endovascular Neurosurgery, University of Patras, University Hospital of Patras, Patras, Achaia, Greece.
General University Hospital of Patras · GR

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundSpontaneous spinal epidural hematomas (SSEHs) are often attributed to anticoagulation. Although they are rare, they may contribute to significant morbidity and mortality. CASE DESCRIPTION: An 83-year-old female with a history of atrial fibrillation on apixaban, presented with 4 days of back pain, progressive lower extremity weakness and urinary retention. When the patient's MRI showed a dorsal thoracolumbar SSEH, the patient underwent a T10-L3 laminectomy for hematoma evacuation. Within 2 postoperative months, her neurological deficits fully resolved.

conclusionApixaban is associated with SSEH resulting in severe neurological morbidity and even mortality. Prompt MRI imaging followed by emergency surgical decompressive surgery may result in full resolution of neurological deficits.

Indexed as

ApixabanSpontaneous spinal epidural hematomaSSEH

Identifiers

PMID34221587
PMCPMC8247671
OpenAlexW3172792575

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.