Evidence map›Paper›PMID 34221518›Full record

ArticleCase reports in endocrinology2021

Successful Treatment of Tumor-Induced Osteomalacia by Multidisciplinary Therapy with Radiation to Intracranial Fibromyxoid Tumor.

Mariangela Massaccesi, Francesco Miccichè, Mario Rigante, Gianluigi Petrone, Elisabetta Lepre, Maria Antonietta Gambacorta, Vincenzo Valentini

Open access · goldAbstract readCase Reports
In one paragraph

Article in Case reports in endocrinology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
0.6field-weighted citation impact, top 34% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed, 5 citations in OpenAlex.

  1. How I treat soft tissue sarcomas.Future oncology (London, England) · 2026
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 2 institutions in 2 countries.

Mariangela MassaccesiFondazione Policlinico Universitario "A. Gemelli" IRCCS, Unità Operativa Complessa di Radioterapia, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Roma, Italy.ORCID https://orcid.org/0000-0002-7740-747X
Francesco MiccichèFondazione Policlinico Universitario "A. Gemelli" IRCCS, Unità Operativa Complessa di Radioterapia, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Roma, Italy.ORCID https://orcid.org/0000-0001-9666-3033
Mario RiganteFondazione Policlinico Universitario "A. Gemelli" IRCCS, Unità Operativa Complessa di Otorinolaringoiatria, Dipartimento di scienze dell'invecchiamento, Neurologiche, Ortopediche e della testa-collo, Roma, Italy.ORCID https://orcid.org/0000-0002-6111-0786
Gianluigi PetroneFondazione Policlinico Universitario "A. Gemelli" IRCCS, Unità Operativa Complessa di Anatomia Patologica, Dipartimento di scienze della salute della donna, del bambino e di sanità pubblica, Roma, Italy.
Elisabetta LepreUniversità Cattolica del Sacro Cuore Facoltà di Medicina e Chirurgia, Roma, Italy.
Maria Antonietta GambacortaFondazione Policlinico Universitario "A. Gemelli" IRCCS, Unità Operativa Complessa di Radioterapia, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Roma, Italy.ORCID https://orcid.org/0000-0001-5455-8737
Vincenzo ValentiniFondazione Policlinico Universitario "A. Gemelli" IRCCS, Unità Operativa Complessa di Radioterapia, Dipartimento di Diagnostica per Immagini, Radioterapia Oncologica ed Ematologia, Roma, Italy.ORCID https://orcid.org/0000-0003-4637-6487
Agostino Gemelli University Polyclinic · ITUniversità Cattolica del Sacro Cuore · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundTumor-induced osteomalacia (TIO) is a rare paraneoplastic syndrome caused by protein fibroblast-growth-factor-23 (FGF-23) secreting tumors. Complete tumor resection is the current standard of care for TIO; however, some patients may develop tumor recurrence. Due to the rarity of this paraneoplastic syndrome, the role of radiotherapy is unclear. This case is worth reporting because it adds to our knowledge some insights about the potential role of radiotherapy in this rare condition.

conclusionsRadiotherapy may provide long-term TIO remission and tumor control, thus being a treatment option in cases where surgery is unfeasible or unsuccessful.

Identifiers

PMID34221518
PMCPMC8219433
OpenAlexW3171888811

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.