Evidence map›Paper›PMID 34221306›Full record

ArticleTherapeutic advances in chronic disease2021

Prevalence, prescriptions, outcomes and costs of type 2 diabetes patients with or without prior coronary artery disease or stroke: a longitudinal 5-year claims-data analysis of over 7 million inhabitants.

Aldo Pietro Maggioni, Letizia Dondi, Felicita Andreotti, Giulia Ronconi, Silvia Calabria, Carlo Piccinni, Antonella Pedrini, Imma Esposito, Nello Martini

Open access · goldAbstract read
In one paragraph

Article in Therapeutic advances in chronic disease, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed, 1 pooled it
1.4field-weighted citation impact, top 17% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 1 synthesis or guideline pooled it, 12 citations in OpenAlex.

  1. Pooled it
  2. Trial
  3. Article
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors at 2 institutions in 1 country.

Aldo Pietro MaggioniFondazione Ricerca e Salute (ReS), Rome, Italy ANMCO Research Center, Fondazione per il Tuo cuore - HCF onlus, Via La Marmora 34, Florence, 50121, Italy.ORCID https://orcid.org/0000-0003-2764-6779
Letizia DondiFondazione Ricerca e Salute (ReS), Rome, Italy.
Felicita AndreottiFondazione Policlinico Universitario A. Gemelli IRCCS, Rome, Italy.
Giulia RonconiFondazione Ricerca e Salute (ReS), Rome, Italy.
Silvia CalabriaFondazione Ricerca e Salute (ReS), Rome, Italy.
Carlo PiccinniFondazione Ricerca e Salute (ReS), Rome, Italy.ORCID https://orcid.org/0000-0002-8648-8961
Antonella PedriniFondazione Ricerca e Salute (ReS), Rome, Italy.
Imma EspositoFondazione Ricerca e Salute (ReS), Rome, Italy.
Nello MartiniFondazione Ricerca e Salute (ReS), Rome, Italy.
Agostino Gemelli University Polyclinic · ITAssociazione Nazionale Medici Cardiologi Ospedalieri · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

aimsTo analyze the prevalence, comorbidities, outcomes and costs of type 2 diabetes mellitus (T2DM) patients with and without coronary artery disease (CAD) or stroke in a population of over 7 million inhabitants.

methodsT2DM patients were identified in 2015 (accrual period) from the Ricerca e Salute (ReS) database linking administrative records to demographics. Based on 2013-2015 information, four cohorts were considered: #1 with CAD and/or stroke; #2 without CAD and/or stroke; #3 with chronic CAD but no myocardial infarction or stroke; #4 with chronic CAD undergoing percutaneous coronary interventions (PCI). Hospitalizations, drugs and other outpatient care were assessed from 2015 to 2017.

resultsThe prevalence of T2DM was 6% (441,085/7,365,954). CAD and/or stroke in the previous 3 years affected 7.5% of T2DM patients (33,153); this cohort was generally older, of male sex, with more comorbidities, prescriptions, and hospital admissions (50.5%

conclusionsThe present analysis points to three areas of potential improvement in T2DM management: (a) guideline-recommended treatment patterns of T2DM patients; (b) three-fold recurrences and costs in T2DM patients with, compared to those without, prior cardiovascular events; (c) high event rates associated with chronic CAD and PCI, warranting specific studies aimed at improved prevention.

Indexed as

big datacoronary artery diseasediabetes mellituspublic health practice

Identifiers

PMID34221306
PMCPMC8221674
OpenAlexW3173558222

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.