ArticleCaspian journal of internal medicine2021
Added diagnostic value of SPECT to evaluate bone metastases in breast cancer patients with normal whole body bone scan.
Article in Caspian journal of internal medicine, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
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3 citing papers in PubMed, 4 citations in OpenAlex.
- The SPECT/CT radiomics-based classification of skeletal metastases and benign bone lesions.Scientific reports · 2026Article
- Single Photon Emission Computed Tomography/X-ray Computed Tomography-based radiomics analysis for diagnosis of bone metastases in patients with breast cancer.Journal of bone oncology · 2025Article
- Accuracy of an Automated Bone Scan Index Measurement System Enhanced by Deep Learning of the Female Skeletal Structure in Patients with Breast Cancer.Nuclear medicine and molecular imaging · 2025Article
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Authors and funding
3 authors at 1 institution in 1 country.
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Abstract
backgroundIn this research, we aimed to survey the added value of single photon emission computed tomography (SPECT) in comparison with planar whole body bone scan to visualize bone metastatic lesions in patients with breast cancer.
methodsA total of 80 patients with breast cancer (invasive ductal carcinoma) were examined with planar whole body bone scan and SPECT imaging using 99mTc-labelled methylene diphosphonate (99mTc-MDP). The patients with abnormal uptakes in SPECT imaging were also investigated with magnetic resonance imaging (MRI).
resultsAmong these 80 patients with normal whole body bone SPECT scan, 19 (23.25%) of them revealed abnormal 99mTc-MDP uptake in skeleton. Furthermore, these 19 patients were subjected to MRI and 3 (3.75%) of them were confirmed with metastatic bone lesion.
conclusionThe obtained data suggest that SPECT possess the added diagnostic over planar whole body bone scan.
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