Evidence map›Paper›PMID 34221147›Full record

ArticleEFSA journal. European Food Safety Authority2021

Safety of 3-FL (3-Fucosyllactose) as a novel food pursuant to Regulation (EU) 2015/2283.

EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA), Dominique Turck, Jacqueline Castenmiller, Stefaan De Henauw, Karen Ildico Hirsch-Ernst, John Kearney, Alexandre Maciuk, Inge Mangelsdorf, Harry J McArdle, Androniki Naska and 17 more

Abstract read
In one paragraph

Article in EFSA journal. European Food Safety Authority, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 19 papers.

0numbers the graph read from it
0cells of the map it votes in
19citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

19 citing papers in PubMed.

  1. Review
  2. Review
  3. Article
  4. Article
  5. Article
  6. Safety of lacto-N-tetraose (LNT) produced by a derivative strain (EFSA journal. European Food Safety Authority · 2025
    Article
  7. Article
  8. Article
  9. Article
  10. Safety of 2'-fucosyllactose (2'-FL) produced by a derivative strain (EFSA journal. European Food Safety Authority · 2023
    Article
  11. Safety of 3-fucosyllactose (3-FL) produced by a derivative strain ofEFSA journal. European Food Safety Authority · 2023
    Article
  12. Article
  13. Article
  14. Article
  15. Article
  16. Safety of 3-fucosyllactose (3-FL) produced by a derivative strain ofEFSA journal. European Food Safety Authority · 2022
    Article
  17. Safety of lacto-N-tetraose (LNT) produced by derivative strains ofEFSA journal. European Food Safety Authority · 2022
    Article
  18. Article
  19. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

27 authors.

EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA)
Dominique Turck
Jacqueline Castenmiller
Stefaan De Henauw
Karen Ildico Hirsch-Ernst
John Kearney
Alexandre Maciuk
Inge Mangelsdorf
Harry J McArdle
Androniki Naska
Carmen Pelaez
Kristina Pentieva
Alfonso Siani
Frank Thies
Sophia Tsabouri
Marco Vinceti
Francesco Cubadda
Thomas Frenzel
Marina Heinonen
Rosangela Marchelli
Monika Neuhäuser-Berthold
Morten Poulsen
Miguel Prieto Maradona
Josef Rudolf Schlatter
Henk van Loveren
Paolo Colombo
Helle Katrine Knutsen

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Following a request from the European Commission, the EFSA Panel on Nutrition, Novel Foods and Food Allergens (NDA) was asked to deliver an opinion on 3-fucosyllactose (3-FL) as a novel food (NF) pursuant to Regulation (EU) 2015/2283. The NF is mainly composed of the human-identical milk oligosaccharide (HiMO) 3-FL but also contains D-lactose and its monomers, L-fucose and a small fraction of other related saccharides. The NF is produced by fermentation with a genetically modified strain of

Indexed as

3‐FL3‐FucosyllactoseHiMOHMOhuman milk oligosaccharidenovel foodsafety

Identifiers

PMID34221147
PMCPMC8243255

What OpenQuestion holds

Textmetadata
LicenceCC BY-ND
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.