Evidence map›Paper›PMID 34221126›Full record

ReviewCardiovascular therapeutics2021

Aberrant Mitochondrial Dynamics: An Emerging Pathogenic Driver of Abdominal Aortic Aneurysm.

Mingqi Ouyang, Mi Wang, Bilian Yu

Open access · goldAbstract readReview
In one paragraph

Review in Cardiovascular therapeutics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
1.8field-weighted citation impact, top 14% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed, 15 citations in OpenAlex.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors at 1 institution in 1 country.

Mingqi OuyangDepartment of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha, 410011 Hunan, China.ORCID https://orcid.org/0000-0002-8021-5938
Mi WangDepartment of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha, 410011 Hunan, China.ORCID https://orcid.org/0000-0002-8478-2366
Bilian YuDepartment of Cardiovascular Medicine, The Second Xiangya Hospital, Central South University, Changsha, 410011 Hunan, China.ORCID https://orcid.org/0000-0002-5701-5487
Central South University · CN

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Abdominal aortic aneurysm (AAA) is defined as a progressive segmental dilation of the abdominal aorta and is associated with high mortality. The characterized features of AAA indicate several underlying mechanisms of AAA formation and progression, including reactive oxygen species production, inflammation, and atherosclerosis. Mitochondrial functions are critical for determining cell fate, and mitochondrial dynamics, especially selective mitochondrial autophagy, which is termed as mitophagy, has emerged as an important player in the pathogenesis of several cardiovascular diseases. The PARKIN/PARIS/PGC1

Indexed as

AnimalsAortic Aneurysm, AbdominalAortic DissectionAtherosclerosisDisease Models, AnimalHumansInflammationMaleMitochondriaMitochondrial DynamicsPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaReactive Oxygen SpeciesUbiquitin-Protein Ligasesparkin proteinPeroxisome Proliferator-Activated Receptor Gamma Coactivator 1-alphaPPARGC1A protein, humanReactive Oxygen SpeciesUbiquitin-Protein Ligases

Identifiers

PMID34221126
PMCPMC8221877
OpenAlexW3175760007

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.