Evidence map›Paper›PMID 34221056›Full record

ArticleResearch in pharmaceutical sciences2021

Validation of an HPLC method for quantification of anti-inflammatory markers in an ethanolic extract of Sahastara and its anti-inflammatory activity

Narin Kakatum, Arunporn Itharat, Weerachai Pipatrattanaseree, Puritat Kanokkangsadal, Neal M Davies

Open access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Research in pharmaceutical sciences, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact, top 95% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed, 2 citations in OpenAlex.

  1. Article
  2. A double-blinded randomized clinical trial: Topical Sahasthara extractJournal of traditional and complementary medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors at 3 institutions in 2 countries.

Narin KakatumFaculty of Medicine, Thammasat University, Pathumthani, 12120, Thailand.
Arunporn ItharatDepartment of Applied Thai Traditional Medicine, Faculty of Medicine, Thammasat University, Pathumthani, 12120, Thailand.
Weerachai PipatrattanasereeRegional Medical Science Center 12 Songkhla, Department of Medical Sciences, Songkhla, 90100, Thailand.
Puritat KanokkangsadalDepartment of Applied Thai Traditional Medicine, Faculty of Medicine, Thammasat University, Pathumthani, 12120, Thailand.
Neal M DaviesFaculty of Pharmacy and Pharmaceutical Sciences, University of Alberta, Edmonton, Canada.
Thammasat University · THSongkhla Rajabhat University · THUniversity of Alberta · CA

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

background and purposeSahastara (SHT) is a traditional Thai medicine for the treatment of musculoskeletal and joint pain. It consists of 21 plant components. A previous study demonstrated the anti-inflammatory activity of SHT on inhibition of nitric oxide production and prostaglandin E EXPERIMENTAL APPROACH: Anti-inflammatory activity was evaluated by inhibitory activity on TNF-α and PGE FINDINGS/

resultsEthanolic extract of SHT exerted inhibitory activity on PGE CONCLUSION AND IMPLICATIONS: Ethanolic extracts of SHT possess anti-inflammatory activity by inhibition of TNF-α and PGE

Indexed as

Anti-inflammatoryHPLCMethod validationPGE2SahastaraTNF-α

Identifiers

PMID34221056
PMCPMC8216163
OpenAlexW3157296371

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-SA
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.