Trial reportCanadian journal of dental hygiene : CJDH = Journal canadien de l'hygiene dentaire : JCHD2021
Effects of an oral hygiene regimen on progression of gingivitis/early periodontitis: A randomized controlled trial.
Trial report in Canadian journal of dental hygiene : CJDH = Journal canadien de l'hygiene dentaire : JCHD, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 18 papers, 2 of them syntheses that pooled it.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
18 citing papers in PubMed, 2 syntheses or guidelines pooled it.
- Clinical implications of dysregulated non-coding RNA expression in periodontitis: evidence synthesis from a systematic review and meta-analysis.Odontology · 2026Pooled it
- A Meta-analysis Comparing Toothbrush Technologies on Gingivitis and Plaque.International dental journal · 2024Pooled it
- Trial
- Source credibility matters: assessing the quality of periodontitis educational content on Chinese social media.BMC oral health · 2026Article
- Migration background, oral hygiene behavior and oral health literacy: findings based on a quota-based sample.Frontiers in oral health · 2026Article
- Identification of Bacterial Networks and Relationship to Host Responses in Early Periodontitis Population over 24 Months.International journal of molecular sciences · 2025Article
- Associations Between Glycemic Control, Self-Reported Gingival Bleeding and Lifestyle Factors in Hospitalized Diabetic Patients.Journal of clinical medicine · 2025Article
- The symptom network of oral health conditions in older populations with oral frailty: a cross-sectional study.BMC oral health · 2025Article
- Association BetweenInfection and drug resistance · 2025Review
- Oral microbiome contributions to metabolic syndrome pathogenesis.Frontiers in microbiology · 2025Review
- Recent advances in hydrogels for treating periodontal diseases and oral mucosal diseases.Frontiers in bioengineering and biotechnology · 2025Review
- Oral Health and Older Adults: A Narrative Review.Dentistry journal · 2024Review
- Innovations in oral hygiene tools: a mini review on recent developments.Frontiers in dental medicine · 2024Review
- Effects of green tea based oral health strategies on disease activity in rheumatoid arthritis.Frontiers in medicine · 2024Article
- Revisiting Oral Antiseptics, Microorganism Targets and Effectiveness.Journal of personalized medicine · 2023Review
- A Study of Oral Health Parameters and the Properties and Composition of Saliva in Oncological Patients with and without Medication-Related Osteonecrosis of the Jaw Who Take Bisphosphonates.Medicina (Kaunas, Lithuania) · 2023Article
- Effect of Toothbrush Bristle Stiffness and Brushing Force on Cleaning Efficacy.Oral health & preventive dentistry · 2023Article
- Systematic Review and Meta Analysis of the Relative Effect on Plaque Index among Pediatric Patients Using Powered (Electric) versus Manual Toothbrushes.Dentistry journal · 2023Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Background: Periodontal disease continues to be prevalent globally, but little clinical research has been undertaken to evaluate the long-term benefits of a daily oral hygiene regimen on progression of gingivitis/early periodontitis. The objective of this study was to evaluate the effects of an oral hygiene regimen (OHR) on the periodontal health of adults in good general health with established gingivitis and early periodontitis over 24 months. Methods: A randomized controlled trial was conducted in adults with established gingivitis, with isolated sites of probing pocket depth >4 mm. Study participants were randomized to the OHR (bioavailable stannous fluoride dentifrice, oscillating-rotating electric toothbrush, cetylpyridinium chloride rinse, and floss; P&G) or usual care products (sodium fluoride dentifrice and manual toothbrush; P&G) groups. At baseline and every 6 months, gingivitis and periodontal measures were assessed and a prophylaxis was conducted. The primary outcome was Gingival Bleeding Index-Bleeding Sites (GBI-BS). Analyses used ANCOVA at 5% significance levels. Results: A total of 107 individuals were enrolled; 87 completed the study. Mean GBI-BS, Modified Gingival Index, and Probing Pocket Depth (PPD) scores were significantly lower at each visit for the OHR versus usual care group by 28% to 39%, 12% to 18%, and 6% to 13%, respectively ( Conclusion: Long-term use of the OHR produced significant periodontal health improvements versus the usual care products.
Indexed as
Identifiers
34221032PMC8219070What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.