Evidence map›Paper›PMID 34220946›Full record

ArticleFrontiers in genetics2021

Novel Autophagy-Related Gene Signature Investigation for Patients With Oral Squamous Cell Carcinoma.

Lihong Huang, Xinghao Yu, Zhou Jiang, Ping Zeng

Abstract read
In one paragraph

Article in Frontiers in genetics, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Lihong HuangDepartment of Biostatistics, Zhongshan Hospital, Fudan University, Shanghai, China.
Xinghao YuDepartment of Biostatistics, School of Public Health, Medical College of Soochow University, Suzhou, China.
Zhou JiangDepartment of Epidemiology and Biostatistics, School of Public Health, Xuzhou Medical University, Xuzhou, China.
Ping ZengDepartment of Epidemiology and Biostatistics, School of Public Health, Xuzhou Medical University, Xuzhou, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The correlation between autophagy defects and oral squamous cell carcinoma (OSCC) has been previously studied, but only based on a limited number of autophagy-related genes in cell lines or animal models. The aim of the present study was to analyze differentially expressed autophagy-related genes through The Cancer Genome Atlas (TCGA) database to explore enriched pathways and potential biological function. Based on TCGA database, a signature composed of four autophagy-related genes (

Indexed as

autophagy-related genecox survival analysisoral squamous cell carcinomaprognostic biomarkerthe cancer genome atlas

Identifiers

PMID34220946
PMCPMC8248343

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.