Evidence map›Paper›PMID 34220777›Full record

ArticleFrontiers in microbiology2021

Antibacterial Activity of a Fractionated

Francesco Di Pierro, Valeria Sagheddu, Serena Galletti, Mara Forti, Marina Elli, Alexander Bertuccioli, Simone Gaeta

Registry-linked trialOpen access · goldAbstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Frontiers in microbiology, 2021. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06758804 (Evaluation of the Efficacy of Winterized Pistacia Lentiscus Oil in Reducing Purulent Bacterial Overinfection of Pediatric Rhinitis), which is not on this map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
0.6field-weighted citation impact, top 30% of its field
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT06758804 nacompletednot on this mapstarted 2025, after this paper: background citation

Evaluation of the Efficacy of Winterized Pistacia Lentiscus Oil in Reducing Purulent Bacterial Overinfection of Pediatric Rhinitis: A Multicenter Randomized Controlled Trial

TypeinterventionalSponsorLiaquat University of Medical & Health SciencesRan2025 to 2025Enrolled105ConditionsRhinitis AcuteArmsWinterized Pistacia Lentiscus Oil Nasal Drops (Bactorinol®), Saline Solution (0.9% NaCl)
3 · Its place in the literature

Who cites it

5 citing papers in PubMed, 4 citations in OpenAlex.

  1. Vaginal formulations selectively target Lactobacillus iners and Candida spp. while preserving Lactobacillus crispatus.International microbiology : the official journal of the Spanish Society for Microbiology · 2026
    Article
  2. Review
  3. Article
  4. Article
  5. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors at 3 institutions in 1 country.

Francesco Di PierroVelleja Research, Milan, Italy.
Valeria SaghedduAAT-Advanced Analytical Technologies, Piacenza, Italy.
Serena GallettiAAT-Advanced Analytical Technologies, Piacenza, Italy.
Mara FortiAAT-Advanced Analytical Technologies, Piacenza, Italy.
Marina ElliAAT-Advanced Analytical Technologies, Piacenza, Italy.
Alexander BertuccioliDepartment of Biomolecular Sciences (DISB), University of Urbino, Urbino, Italy.
Simone GaetaDipartimento di Scienze del Farmaco, Università del Piemonte Orientale, Novara, Italy.
Fondazione Poliambulanza Istituto Ospedaliero · ITUniversità degli Studi del Piemonte Orientale “Amedeo Avogadro” · ITUniversity of Urbino · IT

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Previous studies have clearly demonstrated that the addition of lentisk oil (LO) to streptococcal cultures makes it possible to differentiate

Indexed as

H. influenzaelentisk oilM. catarrhalisS. pneumoniaeS. pyogenesS. salivarius K12S. salivarius M18winterizing

Identifiers

PMID34220777
PMCPMC8247648
OpenAlexW3177102756

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.